Interactor 1: ATG13 (O75143)
Autophagy-related protein 13
Gene: ATG13

Interactor 2: ULK1 (O75385)
Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) (hATG1) (Unc-51-like kinase 1)
Gene: ULK1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 0.60 0.769

The method score is based on:

Property Details
Experiments 25126726, 25686248, 29196462, 27617292, 21460634, 27203176, 30853401, 32543267, 23392225, 33499712, 33422265, 32707033, 36736316, 21460630, 23524951, 19597335, 26018823, 18936157, 32668203, 35271311 and 7 others

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Identification Methods enzymatic study, affinity chromatography technology, pull down, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, in-gel kinase assay, cross-linking study
Interaction Type direct interaction, physical association, phosphorylation reaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000045 - autophagosome assembly
GO:0000407 - phagophore assembly site
GO:0005737 - cytoplasm
GO:0005776 - autophagosome
GO:0005789 - endoplasmic reticulum membrane
and 7 others

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Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 517
Hs

1 1050
+ Mm
+ Hs
+ Dm
+ Ce
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024