HitPredict

Interactor 1: HNRC1 (O60812)
Heterogeneous nuclear ribonucleoprotein C-like 1 (hnRNP C-like-1) (hnRNP core protein C-like 1)
Gene: HNRNPCL1

Interactor 2: HNRPC (P07910)
Heterogeneous nuclear ribonucleoproteins C1/C2 (hnRNP C1/C2)
Gene: HNRNPC

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.88	1.00	0.942

Property	Details
Experiments	32296183, 33961781, 34349018, 38334954, 35575683, unassigned1304
Identification Methods	two hybrid, affinity chromatography technology, cross-linking study, two hybrid prey pooling approach, two hybrid array, anti tag coimmunoprecipitation, validated two hybrid
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 293 Hs			1 306
+	Hs
		85521 HNRC3_HUMAN (1-293): 1.1e-99: 296: 93.52		HNRC1_HUMAN (1-306): 2.49e-87: 264: 86.93
+	Hs
		256554 HNRC1_HUMAN (1-293): 9.34e-99: 293: 100.00		HNRC1_HUMAN (1-306): 2.49e-87: 264: 86.93
+	Hs
		85527 HNRC3_HUMAN (1-293): 1.1e-99: 296: 93.52		HNRPC_HUMAN (1-306): 1.27e-83: 255: 100.00
+	Hs
		74386 HNRC3_HUMAN (1-293): 1.1e-99: 296: 93.52		HNRC2_HUMAN (1-306): 3.31e-80: 246: 84.64
+	Hs
		74406 HNRC1_HUMAN (1-293): 9.34e-99: 293: 100.00		HNRC2_HUMAN (1-306): 3.31e-80: 246: 84.64
+	Hs
		74430 HNRC2_HUMAN (1-293): 2.49e-94: 282: 96.25		HNRPC_HUMAN (1-306): 1.27e-83: 255: 100.00
+	Hs
		74385 HNRC2_HUMAN (1-293): 2.49e-94: 282: 96.25		HNRC2_HUMAN (1-306): 3.31e-80: 246: 84.64
+	Hs
		85535 HNRC3_HUMAN (1-293): 1.1e-99: 296: 93.52		RALYL_HUMAN (3-284): 4.2e-66: 210: 52.23
+	Hs
		256639 HNRC1_HUMAN (1-293): 9.34e-99: 293: 100.00		RALYL_HUMAN (3-284): 4.2e-66: 210: 52.23
+	Hs
		256630 HNRC1_HUMAN (1-293): 9.34e-99: 293: 100.00		Q53GL6_HUMAN (2-298): 5.67e-63: 203: 39.74
+	Hs
		256701 HNRC1_HUMAN (1-293): 9.34e-99: 293: 100.00		RALY_HUMAN (2-298): 3.9e-63: 203: 39.87
+	Hs
		74529 HNRC2_HUMAN (1-293): 2.49e-94: 282: 96.25		RALYL_HUMAN (3-284): 4.2e-66: 210: 52.23
+	Hs
		74508 HNRC2_HUMAN (1-293): 2.49e-94: 282: 96.25		Q53GL6_HUMAN (2-298): 5.67e-63: 203: 39.74
+	Hs
		74640 HNRC2_HUMAN (1-293): 2.49e-94: 282: 96.25		RALY_HUMAN (2-298): 3.9e-63: 203: 39.87
+	Hs
		74561 HNRC2_HUMAN (1-293): 2.49e-94: 282: 96.25		SRS12_HUMAN (8-190): 2.15e-34: 127: 20.94