HitPredict

Interactor 1: HNRC2 (B2RXH8)
Heterogeneous nuclear ribonucleoprotein C-like 2 (hnRNP C-like-2)
Gene: HNRNPCL2

Interactor 2: HNRC1 (O60812)
Heterogeneous nuclear ribonucleoprotein C-like 1 (hnRNP C-like-1) (hnRNP core protein C-like 1)
Gene: HNRNPCL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.79	1.00	0.894

Property	Details
Experiments	32296183, 33961781, 35575683, unassigned1304
Identification Methods	two hybrid, affinity chromatography technology, cross-linking study, two hybrid array, two hybrid prey pooling approach, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:1990904 - ribonucleoprotein complex
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 293 Hs			1 293
+	Hs
		85521 HNRC3_HUMAN (1-293): 1.1e-99: 296: 92.15		HNRC1_HUMAN (1-293): 9.34e-99: 293: 100.00
+	Hs
		256554 HNRC1_HUMAN (1-293): 9.34e-99: 293: 96.25		HNRC1_HUMAN (1-293): 9.34e-99: 293: 100.00
+	Hs
		74386 HNRC3_HUMAN (1-293): 1.1e-99: 296: 92.15		HNRC2_HUMAN (1-293): 2.49e-94: 282: 96.25
+	Hs
		74385 HNRC2_HUMAN (1-293): 2.49e-94: 282: 100.00		HNRC2_HUMAN (1-293): 2.49e-94: 282: 96.25
+	Hs
		85527 HNRC3_HUMAN (1-293): 1.1e-99: 296: 92.15		HNRPC_HUMAN (1-293): 8.44e-87: 263: 86.93
+	Hs
		256567 HNRC1_HUMAN (1-293): 9.34e-99: 293: 96.25		HNRPC_HUMAN (1-293): 8.44e-87: 263: 86.93
+	Hs
		74430 HNRC2_HUMAN (1-293): 2.49e-94: 282: 100.00		HNRPC_HUMAN (1-293): 8.44e-87: 263: 86.93
+	Hs
		85535 HNRC3_HUMAN (1-293): 1.1e-99: 296: 92.15		RALYL_HUMAN (2-271): 1.34e-72: 226: 48.44
+	Hs
		256639 HNRC1_HUMAN (1-293): 9.34e-99: 293: 96.25		RALYL_HUMAN (2-271): 1.34e-72: 226: 48.44
+	Hs
		74529 HNRC2_HUMAN (1-293): 2.49e-94: 282: 100.00		RALYL_HUMAN (2-271): 1.34e-72: 226: 48.44
+	Hs
		256701 HNRC1_HUMAN (1-293): 9.34e-99: 293: 96.25		RALY_HUMAN (2-280): 2.8e-66: 211: 40.33
+	Hs
		256630 HNRC1_HUMAN (1-293): 9.34e-99: 293: 96.25		Q53GL6_HUMAN (2-280): 4.07e-66: 210: 40.20
+	Hs
		74640 HNRC2_HUMAN (1-293): 2.49e-94: 282: 100.00		RALY_HUMAN (2-280): 2.8e-66: 211: 40.33
+	Hs
		74508 HNRC2_HUMAN (1-293): 2.49e-94: 282: 100.00		Q53GL6_HUMAN (2-280): 4.07e-66: 210: 40.20
+	Hs
		74561 HNRC2_HUMAN (1-293): 2.49e-94: 282: 100.00		SRS12_HUMAN (12-244): 1.53e-34: 127: 14.94