HitPredict

Interactor 1: HNRC1 (O60812)
Heterogeneous nuclear ribonucleoprotein C-like 1 (hnRNP C-like-1) (hnRNP core protein C-like 1)
Gene: HNRNPCL1

Interactor 2: RALYL (Q86SE5)
RNA-binding Raly-like protein (hRALYL) (Heterogeneous nuclear ribonucleoprotein C-like 3) (hnRNP core protein C-like 3)
Gene: RALYL

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	1.00	0.843

Property	Details
Experiments	32296183, 35575683, unassigned1304
Identification Methods	two hybrid, cross-linking study, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 293 Hs			1 291
+	Hs
		85535 HNRC3_HUMAN (1-293): 1.1e-99: 296: 93.52		RALYL_HUMAN (1-291): 6.94e-70: 219: 100.00
+	Hs
		74529 HNRC2_HUMAN (1-293): 2.49e-94: 282: 96.25		RALYL_HUMAN (1-291): 6.94e-70: 219: 100.00
+	Hs
		85521 HNRC3_HUMAN (1-293): 1.1e-99: 296: 93.52		HNRC1_HUMAN (6-288): 1.76e-53: 177: 46.15
+	Hs
		256554 HNRC1_HUMAN (1-293): 9.34e-99: 293: 100.00		HNRC1_HUMAN (6-288): 1.76e-53: 177: 46.15
+	Hs
		85527 HNRC3_HUMAN (1-293): 1.1e-99: 296: 93.52		HNRPC_HUMAN (6-288): 7.31e-49: 166: 50.52
+	Hs
		256567 HNRC1_HUMAN (1-293): 9.34e-99: 293: 100.00		HNRPC_HUMAN (6-288): 7.31e-49: 166: 50.52
+	Hs
		74386 HNRC3_HUMAN (1-293): 1.1e-99: 296: 93.52		HNRC2_HUMAN (6-288): 2.81e-47: 161: 46.15
+	Hs
		74406 HNRC1_HUMAN (1-293): 9.34e-99: 293: 100.00		HNRC2_HUMAN (6-288): 2.81e-47: 161: 46.15
+	Hs
		256630 HNRC1_HUMAN (1-293): 9.34e-99: 293: 100.00		Q53GL6_HUMAN (1-291): 8.65e-45: 155: 46.08
+	Hs
		256701 HNRC1_HUMAN (1-293): 9.34e-99: 293: 100.00		RALY_HUMAN (1-291): 1.1e-44: 155: 45.73
+	Hs
		74430 HNRC2_HUMAN (1-293): 2.49e-94: 282: 96.25		HNRPC_HUMAN (6-288): 7.31e-49: 166: 50.52
+	Hs
		74385 HNRC2_HUMAN (1-293): 2.49e-94: 282: 96.25		HNRC2_HUMAN (6-288): 2.81e-47: 161: 46.15
+	Hs
		74508 HNRC2_HUMAN (1-293): 2.49e-94: 282: 96.25		Q53GL6_HUMAN (1-291): 8.65e-45: 155: 46.08
+	Hs
		74640 HNRC2_HUMAN (1-293): 2.49e-94: 282: 96.25		RALY_HUMAN (1-291): 1.1e-44: 155: 45.73
+	Hs
		256617 HNRC1_HUMAN (1-293): 9.34e-99: 293: 100.00		TRA2A_HUMAN (3-141): 1.98e-26: 106: 17.01
+	Hs
		74561 HNRC2_HUMAN (1-293): 2.49e-94: 282: 96.25		SRS12_HUMAN (13-237): 5.4e-28: 110: 17.65