HitPredict

Interactor 1: HNRC2 (B2RXH8)
Heterogeneous nuclear ribonucleoprotein C-like 2 (hnRNP C-like-2)
Gene: HNRNPCL2

Interactor 2: HNRPC (P07910)
Heterogeneous nuclear ribonucleoproteins C1/C2 (hnRNP C1/C2)
Gene: HNRNPC

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.88	1.00	0.942

Property	Details
Experiments	32296183, 34349018, 33961781, 35575683, 38334954, unassigned1304
Identification Methods	two hybrid, cross-linking study, affinity chromatography technology, two hybrid array, two hybrid prey pooling approach, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 293 Hs			1 306
+	Hs
		85521 HNRC3_HUMAN (1-293): 1.1e-99: 296: 92.15		HNRC1_HUMAN (1-306): 2.49e-87: 264: 86.93
+	Hs
		256554 HNRC1_HUMAN (1-293): 9.34e-99: 293: 96.25		HNRC1_HUMAN (1-306): 2.49e-87: 264: 86.93
+	Hs
		85527 HNRC3_HUMAN (1-293): 1.1e-99: 296: 92.15		HNRPC_HUMAN (1-306): 1.27e-83: 255: 100.00
+	Hs
		256567 HNRC1_HUMAN (1-293): 9.34e-99: 293: 96.25		HNRPC_HUMAN (1-306): 1.27e-83: 255: 100.00
+	Hs
		74386 HNRC3_HUMAN (1-293): 1.1e-99: 296: 92.15		HNRC2_HUMAN (1-306): 3.31e-80: 246: 84.64
+	Hs
		74406 HNRC1_HUMAN (1-293): 9.34e-99: 293: 96.25		HNRC2_HUMAN (1-306): 3.31e-80: 246: 84.64
+	Hs
		74385 HNRC2_HUMAN (1-293): 2.49e-94: 282: 100.00		HNRC2_HUMAN (1-306): 3.31e-80: 246: 84.64
+	Hs
		85535 HNRC3_HUMAN (1-293): 1.1e-99: 296: 92.15		RALYL_HUMAN (3-284): 4.2e-66: 210: 52.23
+	Hs
		256639 HNRC1_HUMAN (1-293): 9.34e-99: 293: 96.25		RALYL_HUMAN (3-284): 4.2e-66: 210: 52.23
+	Hs
		256630 HNRC1_HUMAN (1-293): 9.34e-99: 293: 96.25		Q53GL6_HUMAN (2-298): 5.67e-63: 203: 39.74
+	Hs
		256701 HNRC1_HUMAN (1-293): 9.34e-99: 293: 96.25		RALY_HUMAN (2-298): 3.9e-63: 203: 39.87
+	Hs
		74529 HNRC2_HUMAN (1-293): 2.49e-94: 282: 100.00		RALYL_HUMAN (3-284): 4.2e-66: 210: 52.23
+	Hs
		74508 HNRC2_HUMAN (1-293): 2.49e-94: 282: 100.00		Q53GL6_HUMAN (2-298): 5.67e-63: 203: 39.74
+	Hs
		74640 HNRC2_HUMAN (1-293): 2.49e-94: 282: 100.00		RALY_HUMAN (2-298): 3.9e-63: 203: 39.87
+	Hs
		74561 HNRC2_HUMAN (1-293): 2.49e-94: 282: 100.00		SRS12_HUMAN (8-190): 2.15e-34: 127: 20.94