HitPredict

Interactor 1: CAND2 (O75155)
Cullin-associated NEDD8-dissociated protein 2 (Cullin-associated and neddylation-dissociated protein 2) (Epididymis tissue protein Li 169) (TBP-interacting protein of 120 kDa B) (TBP-interacting protein 120B) (p120 CAND2)
Gene: CAND2

Interactor 2: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.594

Property	Details
Experiments	25754235, 35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1236 Hs			1 1210
+	Hs
		338076 MTOR_HUMAN (15-1059): 7.2e-43: 174: 13.64		EGFR_HUMAN (1-1210): 0: 1241: 100.00
+	Hs
		155507 TNPO2_HUMAN (427-1168): 2.37e-33: 141: 11.48		EGFR_HUMAN (1-1210): 0: 1241: 100.00
+	Hs
		338800 TNPO1_HUMAN (644-1188): 2.85e-21: 102: 12.74		EGFR_HUMAN (1-1210): 0: 1241: 100.00
+	Hs
		127154 IPO5_HUMAN (613-1160): 5.31e-15: 82.4: 10.47		EGFR_HUMAN (1-1210): 0: 1241: 100.00
+	Hs
		338782 GCN1_HUMAN (8-551): 2.35e-12: 74.3: 13.38		EGFR_HUMAN (1-1210): 0: 1241: 100.00
+	Hs
		383912 TNPO1_HUMAN (644-1188): 2.85e-21: 102: 12.74		ERBB2_HUMAN (5-1200): 0: 1111: 48.49
+	Hs
		435716 TNPO1_HUMAN (644-1188): 2.85e-21: 102: 12.74		IGF1R_HUMAN (354-658): 1.12e-14: 81.4: 18.47
+	Hs
		435712 GCN1_HUMAN (8-551): 2.35e-12: 74.3: 13.38		IGF1R_HUMAN (354-658): 1.12e-14: 81.4: 18.47