HitPredict

Interactor 1: CAND2 (O75155)
Cullin-associated NEDD8-dissociated protein 2 (Cullin-associated and neddylation-dissociated protein 2) (Epididymis tissue protein Li 169) (TBP-interacting protein of 120 kDa B) (TBP-interacting protein 120B) (p120 CAND2)
Gene: CAND2

Interactor 2: GPR17 (Q13304)
Uracil nucleotide/cysteinyl leukotriene receptor (UDP/CysLT receptor) (G-protein coupled receptor 17) (P2Y-like receptor) (R12)
Gene: GPR17

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1236 Hs			1 367
+	Hs
		256774 CAND2_HUMAN (1-1236): 0: 832: 100.00		LPAR4_HUMAN (44-336): 1.91e-83: 259: 31.67
+	Hs
		723340 CAND1_HUMAN (1-1236): 0: 845: 62.09		APJ_HUMAN (32-364): 1.02e-69: 224: 27.79
+	Hs
		256742 CAND2_HUMAN (1-1236): 0: 832: 100.00		CXCR4_HUMAN (28-340): 6.8e-70: 224: 23.27
+	Hs
		126564 CAND2_HUMAN (1-1236): 0: 832: 100.00		P2Y10_HUMAN (61-336): 5.39e-40: 146: 35.69
+	Hs
		1067530 CAND1_HUMAN (1-1236): 0: 845: 62.09		P2RY6_HUMAN (92-343): 6.63e-33: 127: 35.85
+	Hs
		256751 CAND2_HUMAN (1-1236): 0: 832: 100.00		P2RY6_HUMAN (92-343): 6.63e-33: 127: 35.85
+	Hs
		787471 MTOR_HUMAN (15-1059): 7.2e-43: 174: 13.64		GPR17_HUMAN (1-367): 4.06e-90: 276: 100.00
+	Hs
		155568 TNPO2_HUMAN (427-1168): 2.37e-33: 141: 11.48		GPR17_HUMAN (1-367): 4.06e-90: 276: 100.00
+	Hs
		723279 MTOR_HUMAN (15-1059): 7.2e-43: 174: 13.64		APJ_HUMAN (32-364): 1.02e-69: 224: 27.79
+	Hs
		787434 MTOR_HUMAN (15-1059): 7.2e-43: 174: 13.64		CXCR4_HUMAN (28-340): 6.8e-70: 224: 23.27
+	Hs
		723080 GCN1_HUMAN (8-551): 2.35e-12: 74.3: 13.38		OPRM_HUMAN (9-365): 4.73e-73: 234: 21.04
+	Hs
		155548 TNPO2_HUMAN (427-1168): 2.37e-33: 141: 11.48		LPAR6_HUMAN (48-336): 8.83e-47: 164: 32.22
+	Hs
		787517 MTOR_HUMAN (15-1059): 7.2e-43: 174: 13.64		P2RY8_HUMAN (66-365): 1.26e-33: 129: 30.77
+	Hs
		787488 MTOR_HUMAN (15-1059): 7.2e-43: 174: 13.64		P2RY6_HUMAN (92-343): 6.63e-33: 127: 35.85
+	Hs
		155556 TNPO2_HUMAN (427-1168): 2.37e-33: 141: 11.48		PAR2_HUMAN (57-341): 1.38e-42: 154: 33.78
+	Hs
		126557 TNPO2_HUMAN (427-1168): 2.37e-33: 141: 11.48		P2Y10_HUMAN (61-336): 5.39e-40: 146: 35.69
+	Hs
		1067562 TNPO1_HUMAN (644-1188): 2.85e-21: 102: 12.74		P2RY6_HUMAN (92-343): 6.63e-33: 127: 35.85
+	Hs
		876170 GCN1_HUMAN (8-551): 2.35e-12: 74.3: 13.38		PAR2_HUMAN (57-341): 1.38e-42: 154: 33.78
+	Hs
		127275 IPO5_HUMAN (613-1160): 5.31e-15: 82.4: 10.47		P2RY6_HUMAN (92-343): 6.63e-33: 127: 35.85
+	Hs
		91007 E1NZA1_HUMAN (8-551): 2.24e-12: 74.3: 13.38		P2RY6_HUMAN (92-343): 6.63e-33: 127: 35.85