HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: H2B1O (P23527)
Histone H2B type 1-O (H2B-clustered histone 17) (Histone H2B.2) (Histone H2B.n) (H2B/n)
Gene: H2BC17

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35575683
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 685 Hs			1 126
+	Hs
		508099 UBC_HUMAN (1-685): 0: 857: 100.00		H2B2F_HUMAN (1-126): 1.28e-55: 171: 98.41
+	Hs
		449667 UBC_HUMAN (1-685): 0: 857: 100.00		H2B1J_HUMAN (1-126): 5.51e-55: 169: 98.41
+	Hs
		507741 UBC_HUMAN (1-685): 0: 857: 100.00		H2BFS_HUMAN (1-126): 8.83e-55: 169: 96.03
+	Hs
		507791 UBC_HUMAN (1-685): 0: 857: 100.00		H2B1C_HUMAN (1-126): 7.91e-55: 169: 98.41
+	Hs
		508053 UBC_HUMAN (1-685): 0: 857: 100.00		H2B2E_HUMAN (1-126): 4.94e-55: 169: 99.21
+	Hs
		508382 UBC_HUMAN (1-685): 0: 857: 100.00		H2B1H_HUMAN (1-126): 3.4e-55: 169: 99.21
+	Hs
		508512 UBC_HUMAN (1-685): 0: 857: 100.00		H2B1M_HUMAN (1-126): 3.33e-55: 169: 95.24
+	Hs
		256748 UBC_HUMAN (1-685): 0: 857: 100.00		H2B1K_HUMAN (1-126): 1.05e-54: 168: 97.62
+	Hs
		507591 UBC_HUMAN (1-685): 0: 857: 100.00		H2B1B_HUMAN (1-126): 1.21e-54: 168: 97.62
+	Hs
		507744 UBC_HUMAN (1-685): 0: 857: 100.00		H2B1D_HUMAN (1-126): 2.26e-54: 168: 97.62
+	Hs
		508510 UBC_HUMAN (1-685): 0: 857: 100.00		H2B1N_HUMAN (1-126): 2.24e-54: 168: 97.62
+	Hs
		508513 UBC_HUMAN (1-685): 0: 857: 100.00		H2B1L_HUMAN (1-126): 2.07e-53: 165: 96.83
+	Hs
		508268 UBC_HUMAN (1-685): 0: 857: 100.00		H2B3B_HUMAN (1-126): 1.11e-52: 163: 96.83
+	Hs
		508392 UBC_HUMAN (1-685): 0: 857: 100.00		H2B1A_HUMAN (1-126): 8.21e-48: 151: 85.04
+	Sc
		381366 UBI4P_YEAST (381-685): 4.09e-126: 380: 95.74		H2B2_YEAST (3-125): 3.1e-41: 134: 71.55
+	Dm
		380896 R9PY16_DROME (457-685): 1.03e-83: 268: 90.39		H2B_DROME (36-126): 5.93e-47: 149: 95.60
+	Hs
		659885 RS27A_HUMAN (609-684): 7.26e-41: 148: 100.00		H2B1O_HUMAN (1-126): 1.76e-55: 170: 100.00
+	Hs
		449700 RS27A_HUMAN (609-684): 7.26e-41: 148: 100.00		H2B1J_HUMAN (1-126): 5.51e-55: 169: 98.41
+	Hs
		256822 RS27A_HUMAN (609-684): 7.26e-41: 148: 100.00		H2B1K_HUMAN (1-126): 1.05e-54: 168: 97.62
+	Hs
		754785 RS27A_HUMAN (609-684): 7.26e-41: 148: 100.00		H2B1B_HUMAN (1-126): 1.21e-54: 168: 97.62