HitPredict

Interactor 1: UBB (P0CG47)
Polyubiquitin-B [Cleaved into: Ubiquitin]
Gene: UBB

Interactor 2: H2B1O (P23527)
Histone H2B type 1-O (H2B-clustered histone 17) (Histone H2B.2) (Histone H2B.n) (H2B/n)
Gene: H2BC17

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	35575683, 39358380
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 229 Hs			1 126
+	Hs
		507223 UBB_HUMAN (1-229): 2.65e-99: 289: 100.00		H2B2F_HUMAN (1-126): 1.28e-55: 171: 98.41
+	Hs
		449666 UBB_HUMAN (1-229): 2.65e-99: 289: 100.00		H2B1J_HUMAN (1-126): 5.51e-55: 169: 98.41
+	Hs
		507132 UBB_HUMAN (1-229): 2.65e-99: 289: 100.00		H2BFS_HUMAN (1-126): 8.83e-55: 169: 96.03
+	Hs
		507213 UBB_HUMAN (1-229): 2.65e-99: 289: 100.00		H2B2E_HUMAN (1-126): 4.94e-55: 169: 99.21
+	Hs
		507300 UBB_HUMAN (1-229): 2.65e-99: 289: 100.00		H2B1H_HUMAN (1-126): 3.4e-55: 169: 99.21
+	Hs
		507339 UBB_HUMAN (1-229): 2.65e-99: 289: 100.00		H2B1M_HUMAN (1-126): 3.33e-55: 169: 95.24
+	Hs
		256747 UBB_HUMAN (1-229): 2.65e-99: 289: 100.00		H2B1K_HUMAN (1-126): 1.05e-54: 168: 97.62
+	Hs
		507096 UBB_HUMAN (1-229): 2.65e-99: 289: 100.00		H2B1B_HUMAN (1-126): 1.21e-54: 168: 97.62
+	Hs
		507134 UBB_HUMAN (1-229): 2.65e-99: 289: 100.00		H2B1D_HUMAN (1-126): 2.26e-54: 168: 97.62
+	Hs
		507338 UBB_HUMAN (1-229): 2.65e-99: 289: 100.00		H2B1N_HUMAN (1-126): 2.24e-54: 168: 97.62
+	Hs
		507537 UBC_HUMAN (1-228): 7.54e-92: 285: 100.00		H2B1O_HUMAN (1-126): 1.76e-55: 170: 100.00
+	Hs
		449667 UBC_HUMAN (1-228): 7.54e-92: 285: 100.00		H2B1J_HUMAN (1-126): 5.51e-55: 169: 98.41
+	Hs
		507340 UBB_HUMAN (1-229): 2.65e-99: 289: 100.00		H2B1L_HUMAN (1-126): 2.07e-53: 165: 96.83
+	Hs
		507741 UBC_HUMAN (1-228): 7.54e-92: 285: 100.00		H2BFS_HUMAN (1-126): 8.83e-55: 169: 96.03
+	Hs
		507791 UBC_HUMAN (1-228): 7.54e-92: 285: 100.00		H2B1C_HUMAN (1-126): 7.91e-55: 169: 98.41
+	Hs
		256748 UBC_HUMAN (1-228): 7.54e-92: 285: 100.00		H2B1K_HUMAN (1-126): 1.05e-54: 168: 97.62
+	Hs
		507591 UBC_HUMAN (1-228): 7.54e-92: 285: 100.00		H2B1B_HUMAN (1-126): 1.21e-54: 168: 97.62
+	Hs
		507744 UBC_HUMAN (1-228): 7.54e-92: 285: 100.00		H2B1D_HUMAN (1-126): 2.26e-54: 168: 97.62
+	Hs
		507273 UBB_HUMAN (1-229): 2.65e-99: 289: 100.00		H2B3B_HUMAN (1-126): 1.11e-52: 163: 96.83
+	Hs
		507302 UBB_HUMAN (1-229): 2.65e-99: 289: 100.00		H2B1A_HUMAN (1-126): 8.21e-48: 151: 85.04