HitPredict

Interactor 1: F262 (O60825)
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 (6PF-2-K/Fru-2,6-P2ase 2) (PFK/FBPase 2) (6PF-2-K/Fru-2,6-P2ase heart-type isozyme) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)]
Gene: PFKFB2

Interactor 2: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.90	0.60	0.736

Property	Details
Experiments	12853467, 33961781, 35271311, 36931259, 28514442, unassigned3799
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 505 Hs			1 245
+	Hs
		257041 F262_HUMAN (1-505): 0: 752: 100.00		1433E_HUMAN (2-243): 1.32e-144: 406: 63.53
+	Hs
		257042 F262_HUMAN (1-505): 0: 752: 100.00		1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59
+	Hs
		257036 F262_HUMAN (1-505): 0: 752: 100.00		1433B_HUMAN (1-242): 5.04e-139: 391: 81.82
+	Hs
		257045 F262_HUMAN (1-505): 0: 752: 100.00		1433F_HUMAN (2-242): 7.19e-106: 307: 71.43
+	Hs
		257040 F262_HUMAN (1-505): 0: 752: 100.00		1433G_HUMAN (1-242): 5.51e-105: 305: 70.33
+	Hs
		691051 F263_HUMAN (6-480): 0: 654: 70.44		1433T_HUMAN (1-245): 9.51e-142: 398: 100.00
+	Hs
		990278 F263_HUMAN (6-480): 0: 654: 70.44		1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59
+	Hs
		729873 F263_HUMAN (6-480): 0: 654: 70.44		1433B_HUMAN (1-242): 5.04e-139: 391: 81.82
+	Hs
		971578 F264_HUMAN (6-451): 0: 618: 69.51		1433E_HUMAN (2-243): 1.32e-144: 406: 63.53
+	Hs
		691052 F264_HUMAN (6-451): 0: 618: 69.51		1433T_HUMAN (1-245): 9.51e-142: 398: 100.00
+	Hs
		990279 F264_HUMAN (6-451): 0: 618: 69.51		1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59
+	Hs
		729874 F264_HUMAN (6-451): 0: 618: 69.51		1433B_HUMAN (1-242): 5.04e-139: 391: 81.82
+	Hs
		1049332 F263_HUMAN (6-480): 0: 654: 70.44		1433F_HUMAN (2-242): 7.19e-106: 307: 71.43
+	Hs
		966370 F263_HUMAN (6-480): 0: 654: 70.44		1433G_HUMAN (1-242): 5.51e-105: 305: 70.33
+	Hs
		1049333 F264_HUMAN (6-451): 0: 618: 69.51		1433F_HUMAN (2-242): 7.19e-106: 307: 71.43
+	Hs
		966371 F264_HUMAN (6-451): 0: 618: 69.51		1433G_HUMAN (1-242): 5.51e-105: 305: 70.33
+	Hs
		616167 PGAM1_HUMAN (247-450): 5.47e-72: 231: 20.08		1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59
+	Dm
		1019895 Q9VAN7_DROME (249-447): 2.11e-64: 211: 21.20		1433E_DROME (2-242): 6.8e-143: 401: 65.02