HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: F264 (Q16877)
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (6PF-2-K/Fru-2,6-P2ase 4) (PFK/FBPase 4) (6PF-2-K/Fru-2,6-P2ase testis-type isozyme) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)]
Gene: PFKFB4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.643

Property	Details
Experiments	33961781, 28514442, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 246 Hs			1 469
+	Hs
		971578 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		F264_HUMAN (1-469): 0: 680: 100.00
+	Hs
		990279 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		F264_HUMAN (1-469): 0: 680: 100.00
+	Hs
		691052 1433T_HUMAN (3-244): 3.25e-127: 361: 81.82		F264_HUMAN (1-469): 0: 680: 100.00
+	Hs
		257041 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		F262_HUMAN (2-458): 0: 628: 68.63
+	Hs
		257036 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		F262_HUMAN (2-458): 0: 628: 68.63
+	Hs
		257042 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		F262_HUMAN (2-458): 0: 628: 68.63
+	Hs
		729873 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		F263_HUMAN (4-465): 0: 612: 69.55
+	Hs
		990278 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		F263_HUMAN (4-465): 0: 612: 69.55
+	Hs
		966371 1433G_HUMAN (3-246): 1.92e-109: 317: 75.40		F264_HUMAN (1-469): 0: 680: 100.00
+	Hs
		1049333 1433F_HUMAN (4-244): 2.72e-107: 311: 75.51		F264_HUMAN (1-469): 0: 680: 100.00
+	Hs
		257035 1433T_HUMAN (3-244): 3.25e-127: 361: 81.82		F262_HUMAN (2-458): 0: 628: 68.63
+	Hs
		691051 1433T_HUMAN (3-244): 3.25e-127: 361: 81.82		F263_HUMAN (4-465): 0: 612: 69.55
+	Hs
		257040 1433G_HUMAN (3-246): 1.92e-109: 317: 75.40		F262_HUMAN (2-458): 0: 628: 68.63
+	Hs
		257045 1433F_HUMAN (4-244): 2.72e-107: 311: 75.51		F262_HUMAN (2-458): 0: 628: 68.63
+	Hs
		966370 1433G_HUMAN (3-246): 1.92e-109: 317: 75.40		F263_HUMAN (4-465): 0: 612: 69.55
+	Hs
		1049332 1433F_HUMAN (4-244): 2.72e-107: 311: 75.51		F263_HUMAN (4-465): 0: 612: 69.55
+	Hs
		616167 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		PGAM1_HUMAN (247-450): 6.42e-70: 224: 21.26
+	Dm
		1019895 1433E_DROME (3-245): 4.65e-144: 405: 64.90		Q9VAN7_DROME (249-449): 6.06e-63: 206: 17.46
+	Mm
		972270 1433E_MOUSE (3-243): 4.41e-144: 405: 65.43		PGAM5_MOUSE (208-443): 1.28e-51: 177: 19.92