HitPredict

Interactor 1: PDCD6 (O75340)
Programmed cell death protein 6 (Apoptosis-linked gene 2 protein homolog) (ALG-2)
Gene: PDCD6

Interactor 2: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	36244648, 37045861
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	EF-hand_7~Pkinase
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 191 Hs			1 648
+	Hs
		373761 SORCN_HUMAN (25-190): 1.79e-51: 165: 35.88		RAF1_HUMAN (1-648): 0: 652: 100.00
+	Hs
		373671 CAN3_HUMAN (2-188): 8.75e-45: 159: 25.26		RAF1_HUMAN (1-648): 0: 652: 100.00
+	Hs
		373495 CPNS1_HUMAN (2-188): 1.15e-46: 155: 25.38		RAF1_HUMAN (1-648): 0: 652: 100.00
+	Hs
		375035 PEF1_HUMAN (99-190): 3.26e-17: 79: 29.03		RAF1_HUMAN (1-648): 0: 652: 100.00
+	Hs
		488819 CALL5_HUMAN (18-151): 2.44e-12: 63.2: 30.22		ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28