HitPredict

Interactor 1: PROP1 (O75360)
Homeobox protein prophet of Pit-1 (PROP-1) (Pituitary-specific homeodomain factor)
Gene: PROP1

Interactor 2: PROP1 (O75360)
Homeobox protein prophet of Pit-1 (PROP-1) (Pituitary-specific homeodomain factor)
Gene: PROP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.621

The method score is based on:

Property Details
Experiments 36949045
Identification Methods two hybrid
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Homeodomain~Homeodomain
Common GO terms GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
and 15 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 226
Hs

1 226
+ Mm
+ Hs
+ Dm
+ Mm
+ Mm
+ Hs
+ Mm
+ Hs
+ Ce
+ Mm
+ Mm
+ Mm
+ Mm
+ Mm
+ Mm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024