HitPredict

Interactor 1: CUBN (O70244)
Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor)
Gene: CUBN

Interactor 2: CUBN (O70244)
Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor)
Gene: CUBN

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 9153271, 20237569
Identification Methods affinity chromatography technology, cross-linking study, molecular sieving
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains CUB~CUB, CUB~EGF_CA, EGF~EGF, EGF~EGF_CA, EGF~hEGF, EGF_3~EGF_CA, EGF_CA~EGF_CA, EGF_CA~hEGF
Common GO terms GO:0001701 - in utero embryonic development
GO:0005509 - calcium ion binding
GO:0005737 - cytoplasm
GO:0005765 - lysosomal membrane
GO:0005768 - endosome
and 33 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 3623
Rn

1 3623
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Last updated: 11Aug2025