Interactor 1: BMP1 (P13497)
Bone morphogenetic protein 1 (BMP-1) (EC 3.4.24.19) (Mammalian tolloid protein) (mTld) (Procollagen C-proteinase) (PCP)
Gene: BMP1

Interactor 2: NOTC2 (Q04721)
Neurogenic locus notch homolog protein 2 (Notch 2) (hN2) [Cleaved into: Notch 2 extracellular truncation (N2ECD); Notch 2 intracellular domain (N2ICD)]
Gene: NOTCH2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.33 1.00 0.575

The method score is based on:

Property Details
Experiments unassigned3799
Identification Methods anti tag coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains CUB~EGF_CA, EGF~EGF_CA, EGF_CA~EGF_CA, EGF_CA~hEGF, EGF~FXa_inhibition, EGF_CA~FXa_inhibition
Common GO terms GO:0005509 - calcium ion binding
GO:0005576 - extracellular region
GO:0005794 - Golgi apparatus
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 986
Hs

1 2471
+ Hs
+ Dm
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Last updated: 11Aug2025