HitPredict

Interactor 1: SRS10 (O75494)
Serine/arginine-rich splicing factor 10 (40 kDa SR-repressor protein) (SRrp40) (FUS-interacting serine-arginine-rich protein 1) (Splicing factor SRp38) (Splicing factor, arginine/serine-rich 13A) (TLS-associated protein with Ser-Arg repeats) (TASR) (TLS-associated protein with SR repeats) (TLS-associated serine-arginine protein) (TLS-associated SR protein)
Gene: SRSF10

Interactor 2: DYRK2 (Q92630)
Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1)
Gene: DYRK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 262 Hs			1 601
+	Hs
		1043996 SRS12_HUMAN (1-251): 1.31e-38: 137: 46.33		DYR1A_HUMAN (211-537): 2.66e-117: 367: 42.52
+	Hs
		516362 PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35		CDK2_HUMAN (219-543): 6.32e-142: 415: 27.71
+	Hs
		266986 SRS10_HUMAN (1-262): 2.41e-34: 126: 100.00		DYR1A_HUMAN (211-537): 2.66e-117: 367: 42.52
+	Hs
		951961 SRSF3_HUMAN (1-95): 1.17e-25: 100: 35.79		CDK13_HUMAN (3-598): 8.85e-117: 381: 19.87
+	Mm
		554897 TIAR_MOUSE (12-108): 8.8e-20: 89.6: 25.77		KPCE_MOUSE (55-510): 2.32e-124: 385: 16.70
+	Hs
		951958 SRSF3_HUMAN (1-95): 1.17e-25: 100: 35.79		DYR1A_HUMAN (211-537): 2.66e-117: 367: 42.52
+	Hs
		1031320 PABP4_HUMAN (2-99): 3.59e-20: 91.3: 18.37		DYR1A_HUMAN (211-537): 2.66e-117: 367: 42.52
+	Hs
		516508 PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35		DYR1A_HUMAN (211-537): 2.66e-117: 367: 42.52
+	Sc
		376610 PABP_YEAST (2-98): 4.25e-20: 91: 24.74		YAK1_YEAST (117-573): 7.71e-111: 352: 32.27
+	Hs
		833788 SRS12_HUMAN (1-251): 1.31e-38: 137: 46.33		CLK1_HUMAN (204-535): 3.1e-62: 215: 35.80
+	Hs
		266940 SRS10_HUMAN (1-262): 2.41e-34: 126: 100.00		CLK1_HUMAN (204-535): 3.1e-62: 215: 35.80
+	Hs
		833938 SRS12_HUMAN (1-251): 1.31e-38: 137: 46.33		CLK2_HUMAN (204-543): 6.41e-57: 201: 31.56
+	Hs
		267075 SRS10_HUMAN (1-262): 2.41e-34: 126: 100.00		CLK4_HUMAN (204-535): 1.85e-59: 207: 33.71
+	Hs
		266941 SRS10_HUMAN (1-262): 2.41e-34: 126: 100.00		CLK2_HUMAN (204-543): 6.41e-57: 201: 31.56
+	Zm
		16139 A0A1D6GKL8_MAIZE (9-88): 9.09e-31: 114: 36.25		A0A1D6JDK3_MAIZE (161-535): 2.37e-55: 203: 33.63
+	Hs
		833711 SRSF3_HUMAN (1-95): 1.17e-25: 100: 35.79		CLK1_HUMAN (204-535): 3.1e-62: 215: 35.80
+	Hs
		833865 SRSF3_HUMAN (1-95): 1.17e-25: 100: 35.79		CLK2_HUMAN (204-543): 6.41e-57: 201: 31.56
+	At
		847172 SRC33_ARATH (5-244): 1.41e-24: 101: 29.03		AFC2_ARATH (204-538): 2.3e-57: 200: 33.43
+	Zm
		33400 A0A1D6M1U3_MAIZE (5-127): 1.28e-19: 88.5: 27.20		A0A1D6L2E7_MAIZE (199-535): 4.27e-54: 201: 35.19
+	Hs
		516416 PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35		CLK2_HUMAN (204-543): 6.41e-57: 201: 31.56