HitPredict

Interactor 1: SRS10 (O75494)
Serine/arginine-rich splicing factor 10 (40 kDa SR-repressor protein) (SRrp40) (FUS-interacting serine-arginine-rich protein 1) (Splicing factor SRp38) (Splicing factor, arginine/serine-rich 13A) (TLS-associated protein with Ser-Arg repeats) (TASR) (TLS-associated protein with SR repeats) (TLS-associated serine-arginine protein) (TLS-associated SR protein)
Gene: SRSF10

Interactor 2: FZR1 (Q9UM11)
Fizzy-related protein homolog (Fzr) (CDC20-like protein 1) (Cdh1/Hct1 homolog) (hCDH1)
Gene: FZR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33306668
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 262 Hs			1 496
+	Hs
		267038 SRS10_HUMAN (1-262): 2.41e-34: 126: 100.00		FBXW7_HUMAN (87-424): 1.7e-71: 242: 18.68
+	Hs
		964042 SRSF2_HUMAN (4-90): 1.89e-24: 99.3: 45.65		FBXW7_HUMAN (87-424): 1.7e-71: 242: 18.68
+	Hs
		952150 SRSF3_HUMAN (1-95): 1.17e-25: 100: 35.79		NLE1_HUMAN (52-385): 3.28e-60: 207: 16.32
+	Hs
		267045 SRS10_HUMAN (1-262): 2.41e-34: 126: 100.00		SNR40_HUMAN (32-339): 1.33e-49: 175: 15.89
+	Hs
		1288389 PPIE_HUMAN (10-98): 5.42e-30: 115: 31.46		SNR40_HUMAN (32-339): 1.33e-49: 175: 15.89
+	Hs
		952072 SRSF3_HUMAN (1-95): 1.17e-25: 100: 35.79		SNR40_HUMAN (32-339): 1.33e-49: 175: 15.89
+	Hs
		266949 SRS10_HUMAN (1-262): 2.41e-34: 126: 100.00		WDR5_HUMAN (389-496): 1.49e-26: 111: 18.35
+	Hs
		1357188 PPIE_HUMAN (10-98): 5.42e-30: 115: 31.46		FZR1_HUMAN (319-495): 6.65e-25: 109: 18.68
+	Hs
		964033 SRSF2_HUMAN (4-90): 1.89e-24: 99.3: 45.65		POC1B_HUMAN (31-259): 4.34e-30: 124: 13.19
+	Hs
		903196 PABP4_HUMAN (2-99): 3.59e-20: 91.3: 18.37		WDR5_HUMAN (389-496): 1.49e-26: 111: 18.35
+	Hs
		1031495 PABP4_HUMAN (2-99): 3.59e-20: 91.3: 18.37		FZR1_HUMAN (319-495): 6.65e-25: 109: 18.68
+	Hs
		516438 PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35		WDR5_HUMAN (389-496): 1.49e-26: 111: 18.35
+	Mm
		665772 PABP1_MOUSE (2-99): 6.34e-19: 87.9: 17.35		FZR1_MOUSE (319-495): 2.95e-25: 110: 18.68
+	Hs
		516740 PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35		FZR1_HUMAN (319-495): 6.65e-25: 109: 18.68