Interactor 1: EED (O75530)
Polycomb protein EED (hEED) (Embryonic ectoderm development protein) (WD protein associating with integrin cytoplasmic tails 1) (WAIT-1)
Gene: EED

Interactor 2: SUZ12 (Q15022)
Polycomb protein SUZ12 (Chromatin precipitated E2F target 9 protein) (ChET 9 protein) (Joined to JAZF1 protein) (Suppressor of zeste 12 protein homolog)
Gene: SUZ12

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 1.00 0.991

The method score is based on:

Property Details
Experiments 20075857, 24457600, 28514442, 27338022, 27705803, 27634302, 31281901, 33961781, 35016035, 36652389, 19026781, 18483221, 26496610, 23280602, 28320739, 31786184, 24981860, 12435631, 15385962, 15225548 and 7 others

more...

Identification Methods affinity chromatography technology, cross-linking study, pull down, biochemical, proximity labelling technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains VEFS-Box~WD40
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001222 - transcription corepressor binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0008047 - enzyme activator activity
and 2 others

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Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 441
Hs

1 739
+ Mm
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Dm
+ At
+ At

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Last updated: 15 Jul 2024