HitPredict

Interactor 1: SRGP2 (O75044)
SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2) (Rho GTPase-activating protein 34)
Gene: SRGAP2

Interactor 2: PROF1 (P07737)
Profilin-1 (Epididymis tissue protein Li 184a) (Profilin I)
Gene: PFN1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0031267 - small GTPase binding GO:0098978 - glutamatergic synapse
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1071 Hs			1 140
+	Hs
		459615 RHG29_HUMAN (29-1011): 1.46e-96: 335: 16.23		PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00
+	Hs
		459421 BCR_HUMAN (25-664): 6.53e-78: 281: 14.82		PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00
+	Hs
		459636 RHG17_HUMAN (244-1048): 8.32e-79: 279: 13.50		PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00
+	Hs
		459626 RHG21_HUMAN (349-1027): 2.56e-76: 278: 15.15		PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00
+	Hs
		73986 MYO9A_HUMAN (80-935): 5.83e-76: 277: 14.80		PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00
+	Hs
		459675 RHG24_HUMAN (357-974): 2.05e-70: 252: 16.64		PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00
+	Hs
		459767 RHG35_HUMAN (502-649): 2.57e-17: 90.1: 31.76		PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00
+	Hs
		459612 RHGBB_HUMAN (504-671): 5.01e-18: 87: 33.14		PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00
+	Hs
		459567 RHG05_HUMAN (500-649): 3.86e-15: 82.8: 30.67		PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00