Interactor 1: SRGP2 (O75044)
SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2) (Rho GTPase-activating protein 34)
Gene: SRGAP2
Interactor 2: TIAM1 (Q13009)
Rho guanine nucleotide exchange factor TIAM1 (T-lymphoma invasion and metastasis-inducing protein 1) (TIAM-1)
Gene: TIAM1
Species: Homo sapiens
Source: biogrid
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 27173435 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PH~SH3_1, RhoGEF~SH3_1 |
| Common GO terms | GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0051056 - regulation of small GTPase mediated signal transduction |
| Homologous interactions | 7 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025