HitPredict

Interactor 1: SDC3 (O75056)
Syndecan-3 (SYND3)
Gene: SDC3

Interactor 2: ITB4 (P16144)
Integrin beta-4 (GP150) (CD antigen CD104)
Gene: ITGB4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	20181947
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0009986 - cell surface GO:0016477 - cell migration
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 442 Hs			1 1822
+	Hs
		592625 SDC2_HUMAN (293-442): 1.27e-25: 105: 31.14		ITB4_HUMAN (1-1822): 0: 1224: 100.00
+	Hs
		592615 SDC1_HUMAN (152-442): 1.89e-23: 102: 25.17		ITB4_HUMAN (1-1822): 0: 1224: 100.00
+	Mm
		59087 SDC4_MOUSE (312-442): 1.84e-27: 110: 35.21		ITB4_MOUSE (1-1822): 0: 1176: 87.72
+	Mm
		59089 SDC1_MOUSE (156-442): 2.83e-25: 107: 28.33		ITB4_MOUSE (1-1822): 0: 1176: 87.72
+	Dm
		598295 SDC_DROME (267-442): 2.45e-25: 109: 22.78		LAR_DROME (828-1770): 3.14e-72: 271: 12.45
+	Hs
		1361883 TITIN_HUMAN (84-322): 1.07e-09: 63.2: 15.48		NEO1_HUMAN (916-1821): 1.02e-81: 300: 12.63
+	Hs
		158525 NCAN_HUMAN (10-396): 1.5e-29: 124: 15.87		PTPRF_HUMAN (818-1321): 1.23e-25: 118: 11.78
+	Hs
		158528 NCAN_HUMAN (10-396): 1.5e-29: 124: 15.87		TENA_HUMAN (981-1394): 2.79e-22: 107: 9.86
+	Hs
		158532 NCAN_HUMAN (10-396): 1.5e-29: 124: 15.87		TENR_HUMAN (468-630): 9.12e-15: 82.4: 33.70
+	Mm
		205773 SDC4_MOUSE (312-442): 1.84e-27: 110: 35.21		ITB1_MOUSE (563-755): 2.08e-10: 67.8: 11.56
+	Ce
		145091 UNC89_CAEEL (89-383): 8.37e-09: 60.1: 12.69		UNC22_CAEEL (1089-1742): 1.71e-22: 108: 13.88
+	Hs
		612100 TITIN_HUMAN (84-322): 1.07e-09: 63.2: 15.48		ITB5_HUMAN (569-820): 3.84e-11: 70.5: 10.99
+	Hs
		1361879 TITIN_HUMAN (84-322): 1.07e-09: 63.2: 15.48		TITIN_HUMAN (940-1645): 1.75e-10: 69: 12.15