Interactor 1: FZD7 (O75084)
Frizzled-7 (Fz-7) (hFz7) (FzE3)
Gene: FZD7

Interactor 2: LRP6 (O75581)
Low-density lipoprotein receptor-related protein 6 (LRP-6)
Gene: LRP6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.39 0.60 0.484

The method score is based on:

Property Details
Experiments 36994853
Identification Methods comigration in sds page, comigration in gel electrophoresis
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005109 - frizzled binding
GO:0005886 - plasma membrane
GO:0017147 - Wnt-protein binding
GO:0042813 - Wnt receptor activity
GO:0045893 - positive regulation of DNA-templated transcription
and 1 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 574
Hs

1 1613
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025