Protein: FZD8
Frizzled-8 (Fz-8) (hFz8)

Gene: FZD8
Organism: Homo sapiens
Interactions: 33
UniProt ID: Q9H461

Gene Ontology (top 5):
GO:0001525 - angiogenesis
GO:0004930 - G protein-coupled receptor activity
GO:0005102 - signaling receptor binding
GO:0005794 - Golgi apparatus
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

411165

WNT1
Proto-oncogene Wnt-1

1

20

Small-scale

0.647

High

1371436

DVL3
Segment polarity protein dishevelled homolog DVL-3

1

20

Small-scale

0.618

High

287609

LRP6
Low-density lipoprotein receptor-related protein 6

2

5

Small-scale

0.595

High

869671

SC6A8
Sodium- and chloride-dependent creatine transporter 1

2

2

Small-scale

0.571

High

132662

UPK1A
Uroplakin-1a

1

9

High-throughput

0.536

High

349567

TSN15
Tetraspanin-15

1

4

High-throughput

0.536

High

663531

FSHR
Follicle-stimulating hormone receptor

1

1

High-throughput

0.536

High

771816

SCN4A
Sodium channel protein type 4 subunit alpha

1

4

High-throughput

0.536

High

1333605

SIDT2
SID1 transmembrane family member 2

1

1

High-throughput

0.536

High

1393204

TM169
Transmembrane protein 169

1

3

High-throughput

0.536

High

1277988

KCNKI
Potassium channel subfamily K member 18

1

0

High-throughput

0.513

High

140436

SDCB1
Syntenin-1

1

19

Small-scale

0.501

High

274917

LRP5
Low-density lipoprotein receptor-related protein 5

1

5

Small-scale

0.501

High

1229082

RNF43
E3 ubiquitin-protein ligase RNF43

1

6

Small-scale

0.479

High

1433159

EPN1
Epsin-1

1

1

Small-scale

0.479

High

303285

S22A5
Organic cation/carnitine transporter 2

1

3

High-throughput

0.445

High

663635

SC6A2
Sodium-dependent noradrenaline transporter

1

2

High-throughput

0.445

High

868066

OR1D4
Olfactory receptor 1D4

1

5

High-throughput

0.445

High

1090033

NTCP2
Ileal sodium/bile acid cotransporter

1

1

High-throughput

0.445

High

1186046

SOAT
Sodium-dependent organic anion transporter

1

1

High-throughput

0.445

High

1308791

S41A1
Solute carrier family 41 member 1

1

1

High-throughput

0.445

High

1392715

S39AD
Zinc transporter ZIP13

1

5

High-throughput

0.445

High

1433157

S52A3
Solute carrier family 52, riboflavin transporter, member 3

1

1

High-throughput

0.445

High

1433158

S22AE
Solute carrier family 22 member 14

1

3

High-throughput

0.445

High

1178993

SC5A9
Sodium/glucose cotransporter 4

1

0

High-throughput

0.426

High

1249747

S49A3
Solute carrier family 49 member A3

1

0

High-throughput

0.426

High

1292374

UN93A
Protein unc-93 homolog A

1

0

High-throughput

0.426

High

1330792

S35G3
Solute carrier family 35 member G3

1

0

High-throughput

0.426

High

1419368

GTR11
Solute carrier family 2, facilitated glucose transporter member 11

1

0

High-throughput

0.426

High

1433156

IPPK
Inositol-pentakisphosphate 2-kinase

2

0

High-throughput

0.328

High

904383

BRCA2
Breast cancer type 2 susceptibility protein

1

0

Small-scale

0.249

Low

1308213

PLD3
5'-3' exonuclease PLD3

1

0

High-throughput

0.249

Low

1259246

NCKX5
Sodium/potassium/calcium exchanger 5

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025