HitPredict

Interactor 1: U520 (O75643)
U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.4.13) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog) (U5 snRNP-specific 200 kDa protein) (U5-200KD)
Gene: SNRNP200

Interactor 2: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.88	0.60	0.729

Property	Details
Experiments	17353931, 29467282, 30415952, 35013218, 36424410, 17314511
Identification Methods	affinity chromatography technology, proximity labelling technology, anti bait coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 2136 Hs			1 454
+	Hs
		272003 U520_HUMAN (1-2136): 0: 1844: 100.00		MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40
+	Hs
		347311 ASCC3_HUMAN (56-2134): 0: 1449: 38.34		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		345867 DDX5_HUMAN (1241-1718): 1.86e-108: 362: 12.47		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		347225 DDX42_HUMAN (231-900): 2.59e-103: 357: 13.42		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		347494 DDX17_HUMAN (405-901): 6.31e-105: 356: 13.72		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		346148 MTREX_HUMAN (1287-2037): 2.62e-101: 354: 18.12		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		346863 SKI2_HUMAN (1292-1738): 8.82e-97: 344: 24.21		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		347773 DDX23_HUMAN (1241-1748): 1.71e-87: 307: 14.36		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		224742 DHX16_HUMAN (1094-2008): 1.27e-67: 252: 11.11		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		347475 PRP16_HUMAN (1317-1920): 4.33e-65: 246: 11.76		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		378997 DDX5_HUMAN (1241-1718): 1.86e-108: 362: 12.47		MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40
+	Hs
		379679 DDX17_HUMAN (405-901): 6.31e-105: 356: 13.72		MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40
+	Hs
		379096 MTREX_HUMAN (1287-2037): 2.62e-101: 354: 18.12		MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40
+	Hs
		379805 DDX23_HUMAN (1241-1748): 1.71e-87: 307: 14.36		MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40