HitPredict

Interactor 1: GP182 (O15218)
G-protein coupled receptor 182
Gene: GPR182

Interactor 2: CTR2 (P52569)
Cationic amino acid transporter 2 (CAT-2) (CAT2) (Low affinity cationic amino acid transporter 2) (Solute carrier family 7 member 2)
Gene: SLC7A2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 404 Hs			1 658
+	Hs
		854868 CXCR4_HUMAN (25-343): 3.18e-72: 231: 22.36		CTR2_HUMAN (1-658): 3.63e-180: 528: 100.00
+	Hs
		854883 GPR17_HUMAN (1-362): 6.63e-71: 228: 23.72		CTR2_HUMAN (1-658): 3.63e-180: 528: 100.00
+	Hs
		171941 GP182_HUMAN (1-404): 1.17e-85: 268: 100.00		CTR1_HUMAN (2-615): 2.95e-150: 450: 61.07
+	Hs
		208469 OX2R_HUMAN (19-366): 4.43e-70: 229: 17.25		CTR3_HUMAN (2-619): 3.47e-132: 404: 56.45
+	Hs
		598928 FPR1_HUMAN (54-357): 2.05e-24: 104: 26.28		CTR2_HUMAN (1-658): 3.63e-180: 528: 100.00
+	Hs
		626506 FPR2_HUMAN (53-346): 7.4e-23: 100: 26.33		CTR2_HUMAN (1-658): 3.63e-180: 528: 100.00
+	Hs
		172150 GP182_HUMAN (1-404): 1.17e-85: 268: 100.00		YLAT2_HUMAN (11-487): 1.1e-97: 311: 18.20
+	Hs
		134363 ACKR2_HUMAN (43-331): 2.65e-32: 127: 33.33		CTR1_HUMAN (2-615): 2.95e-150: 450: 61.07
+	Hs
		723286 APJ_HUMAN (34-397): 3.04e-72: 232: 23.48		S12A2_HUMAN (3-503): 1.6e-91: 310: 12.38
+	Hs
		849636 CCR4_HUMAN (22-371): 3.06e-72: 232: 22.88		S12A5_HUMAN (6-479): 8.05e-91: 307: 11.55
+	Hs
		798442 LPAR6_HUMAN (39-324): 2.15e-24: 104: 24.41		CTR3_HUMAN (2-619): 3.47e-132: 404: 56.45