HitPredict

Interactor 1: BRE1B (O75150)
E3 ubiquitin-protein ligase BRE1B (BRE1-B) (EC 2.3.2.27) (95 kDa retinoblastoma-associated protein) (RBP95) (RING finger protein 40) (RING-type E3 ubiquitin transferase BRE1B)
Gene: RNF40

Interactor 2: RB12B (Q8IXT5)
RNA-binding protein 12B (RNA-binding motif protein 12B)
Gene: RBM12B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1001 Hs			1 1001
+	Hs
		1217877 BRE1A_HUMAN (1-1000): 6.44e-66: 242: 56.49		RB12B_HUMAN (1-1001): 0: 577: 100.00
+	Hs
		157592 CTRO_HUMAN (248-944): 2.52e-10: 67.2: 14.91		RB12B_HUMAN (1-1001): 0: 577: 100.00
+	Hs
		912918 BRE1A_HUMAN (1-1000): 6.44e-66: 242: 56.49		HNRPF_HUMAN (274-503): 5.37e-38: 149: 20.25
+	Sc
		676773 BRE1_YEAST (506-1000): 2.21e-57: 212: 18.77		GBP2_YEAST (157-454): 3.72e-47: 176: 15.61
+	Hs
		272761 BRE1B_HUMAN (1-1001): 6.12e-77: 274: 100.00		RBM12_HUMAN (1-87): 4.05e-19: 95.4: 72.41
+	Hs
		1217919 BRE1A_HUMAN (1-1000): 6.44e-66: 242: 56.49		RBM12_HUMAN (1-87): 4.05e-19: 95.4: 72.41
+	Hs
		157501 CTRO_HUMAN (248-944): 2.52e-10: 67.2: 14.91		NIPBL_HUMAN (538-873): 7.42e-56: 214: 12.61
+	Hs
		157120 CTRO_HUMAN (248-944): 2.52e-10: 67.2: 14.91		HNRPF_HUMAN (274-503): 5.37e-38: 149: 20.25
+	Hs
		157251 CTRO_HUMAN (248-944): 2.52e-10: 67.2: 14.91		TIAR_HUMAN (3-286): 5.37e-22: 101: 10.64
+	Hs
		157504 CTRO_HUMAN (248-944): 2.52e-10: 67.2: 14.91		ESRP1_HUMAN (5-178): 2.04e-17: 89.3: 18.10
+	Hs
		157454 CTRO_HUMAN (248-944): 2.52e-10: 67.2: 14.91		PAP1L_HUMAN (3-155): 3.01e-15: 82.4: 14.74
+	Hs
		157002 CTRO_HUMAN (248-944): 2.52e-10: 67.2: 14.91		HNRH3_HUMAN (5-120): 1.84e-14: 78: 24.58
+	Hs
		157144 CTRO_HUMAN (248-944): 2.52e-10: 67.2: 14.91		HNRH2_HUMAN (5-162): 7.87e-13: 73.8: 25.63
+	Hs
		157845 CTRO_HUMAN (248-944): 2.52e-10: 67.2: 14.91		PABP3_HUMAN (3-155): 3.17e-12: 72.4: 13.46
+	Hs
		156893 CTRO_HUMAN (248-944): 2.52e-10: 67.2: 14.91		PABP1_HUMAN (3-187): 4.5e-12: 72: 14.36
+	Hs
		157298 CTRO_HUMAN (248-944): 2.52e-10: 67.2: 14.91		GRSF1_HUMAN (370-492): 6.43e-12: 71.2: 20.31
+	Hs
		157323 CTRO_HUMAN (248-944): 2.52e-10: 67.2: 14.91		PABP4_HUMAN (3-156): 3.99e-11: 68.9: 11.11
+	Hs
		158029 CTRO_HUMAN (248-944): 2.52e-10: 67.2: 14.91		RBM19_HUMAN (285-575): 6.02e-11: 68.9: 11.59