HitPredict

Interactor 1: CREST (O75177)
Calcium-responsive transactivator (SS18-like protein 1) (SYT homolog 1)
Gene: SS18L1

Interactor 2: SMCA2 (P51531)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 (SAMRCA2) (EC 3.6.4.-) (BRG1-associated factor 190B) (BAF190B) (Probable global transcription activator SNF2L2) (Protein brahma homolog) (hBRM) (SNF2-alpha)
Gene: SMARCA2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	31753913, 24981860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	QLQ~SSXT
Common GO terms	GO:0003713 - transcription coactivator activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045893 - positive regulation of DNA-templated transcription GO:0045944 - positive regulation of transcription by RNA polymerase II and 1 others more... GO:0071565 - nBAF complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 396 Hs			1 1590
+	Hs
		903165 SSXT_HUMAN (1-396): 5.48e-68: 222: 53.83		SMCA2_HUMAN (1-1590): 0: 1105: 100.00
+	Mm
		1231593 CREST_MOUSE (1-396): 4.66e-78: 248: 89.80		SMCA2_MOUSE (1-1590): 0: 1073: 94.00
+	Hs
		62704 A4PIW0_HUMAN (1-342): 3.8e-54: 187: 47.65		SMCA2_HUMAN (1-1590): 0: 1105: 100.00
+	Mm
		1189457 CREST_MOUSE (1-396): 4.66e-78: 248: 89.80		SMCA4_MOUSE (1-1588): 0: 1001: 72.25
+	Hs
		903274 S18L2_HUMAN (1-73): 9.9e-40: 137: 60.27		SMCA2_HUMAN (1-1590): 0: 1105: 100.00
+	Hs
		273986 CREST_HUMAN (1-396): 3.17e-78: 248: 100.00		SMCA4_HUMAN (1-1588): 0: 991: 71.12
+	Mm
		1189442 SSXT_MOUSE (1-396): 7.29e-71: 230: 56.22		SMCA4_MOUSE (1-1588): 0: 1001: 72.25
+	Rn
		93310 D4ABC5_RAT (1-396): 7.25e-70: 227: 56.22		SMCA4_RAT (1-1588): 0: 1001: 72.31
+	Hs
		903372 SSXT_HUMAN (1-396): 5.48e-68: 222: 53.83		SMCA4_HUMAN (1-1588): 0: 991: 71.12
+	Hs
		62693 A4PIV7_HUMAN (1-388): 2.75e-63: 212: 52.93		SMCA4_HUMAN (1-1588): 0: 991: 71.12
+	Hs
		62700 A4PIV9_HUMAN (1-388): 2.69e-63: 212: 52.93		SMCA4_HUMAN (1-1588): 0: 991: 71.12
+	Mm
		1189445 SMCA2_MOUSE (74-384): 6.61e-36: 142: 17.93		SMCA4_MOUSE (1-1588): 0: 1001: 72.25
+	Hs
		903511 S18L2_HUMAN (1-73): 9.9e-40: 137: 60.27		SMCA4_HUMAN (1-1588): 0: 991: 71.12
+	Hs
		903105 SMCA2_HUMAN (74-384): 1.05e-26: 114: 15.67		SMCA4_HUMAN (1-1588): 0: 991: 71.12
+	Mm
		1189425 SMCA4_MOUSE (74-384): 3.4e-11: 67.4: 12.96		SMCA4_MOUSE (1-1588): 0: 1001: 72.25
+	Hs
		243645 SSXT_HUMAN (1-396): 5.48e-68: 222: 53.83		SMCA5_HUMAN (584-1564): 0: 826: 26.28
+	Hs
		62701 A4PIW0_HUMAN (1-342): 3.8e-54: 187: 47.65		SMCA5_HUMAN (584-1564): 0: 826: 26.28
+	Hs
		903157 SMCA2_HUMAN (74-384): 1.05e-26: 114: 15.67		CHD4_HUMAN (386-1589): 0: 766: 22.34
+	Hs
		903145 SMCA2_HUMAN (74-384): 1.05e-26: 114: 15.67		CHD3_HUMAN (392-1589): 0: 740: 22.81
+	Mm
		59402 SMCA4_MOUSE (74-384): 3.4e-11: 67.4: 12.96		CHD7_MOUSE (27-637): 3.76e-19: 97.1: 9.22