HitPredict

Interactor 1: A4PIV9 (A4PIV9)
Fusion protein SYT-SSX2
Gene: SYT-SSX2

Interactor 2: SMCA4 (P51532)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4 (SMARCA4) (EC 3.6.4.-) (BRG1-associated factor 190A) (BAF190A) (Mitotic growth and transcription activator) (Protein BRG-1) (Protein brahma homolog 1) (SNF2-beta) (Transcription activator BRG1)
Gene: SMARCA4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	23540691
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	QLQ~SSXT
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 488 Hs			1 1647
+	Hs
		62693 A4PIV7_HUMAN (1-488): 5e-84: 269: 97.34		SMCA4_HUMAN (1-1647): 0: 1088: 100.00
+	Hs
		903372 SSXT_HUMAN (1-411): 4.07e-61: 207: 99.76		SMCA4_HUMAN (1-1647): 0: 1088: 100.00
+	Mm
		1189442 SSXT_MOUSE (1-411): 4.12e-64: 215: 95.86		SMCA4_MOUSE (1-1647): 0: 1050: 96.66
+	Rn
		93310 D4ABC5_RAT (1-411): 9.03e-62: 209: 94.65		SMCA4_RAT (1-1647): 0: 1050: 96.60
+	Hs
		273986 CREST_HUMAN (1-411): 1.4e-38: 146: 54.99		SMCA4_HUMAN (1-1647): 0: 1088: 100.00
+	Mm
		1189457 CREST_MOUSE (1-411): 3.38e-43: 159: 56.69		SMCA4_MOUSE (1-1647): 0: 1050: 96.66
+	Hs
		62704 A4PIW0_HUMAN (1-488): 1.61e-74: 243: 93.65		SMCA2_HUMAN (40-1647): 0: 958: 72.59
+	Hs
		903165 SSXT_HUMAN (1-411): 4.07e-61: 207: 99.76		SMCA2_HUMAN (40-1647): 0: 958: 72.59
+	Mm
		1231593 CREST_MOUSE (1-411): 3.38e-43: 159: 56.69		SMCA2_MOUSE (40-1647): 0: 962: 72.98
+	Hs
		273985 CREST_HUMAN (1-411): 1.4e-38: 146: 54.99		SMCA2_HUMAN (40-1647): 0: 958: 72.59
+	Hs
		903168 SSX2_HUMAN (389-488): 2.47e-32: 123: 83.17		SMCA2_HUMAN (40-1647): 0: 958: 72.59
+	Hs
		62701 A4PIW0_HUMAN (1-488): 1.61e-74: 243: 93.65		SMCA5_HUMAN (594-1622): 0: 815: 27.27
+	Hs
		243645 SSXT_HUMAN (1-411): 4.07e-61: 207: 99.76		SMCA5_HUMAN (594-1622): 0: 815: 27.27
+	Hs
		703301 BPTF_HUMAN (29-421): 8.88e-25: 110: 13.28		SMCA1_HUMAN (639-1621): 0: 830: 29.20
+	Hs
		243649 SSX2_HUMAN (389-488): 2.47e-32: 123: 83.17		SMCA5_HUMAN (594-1622): 0: 815: 27.27
+	Hs
		243614 BPTF_HUMAN (29-421): 8.88e-25: 110: 13.28		SMCA5_HUMAN (594-1622): 0: 815: 27.27
+	Hs
		1086752 BPTF_HUMAN (29-421): 8.88e-25: 110: 13.28		CHD3_HUMAN (270-1647): 0: 733: 21.04
+	Hs
		130451 SPT5H_HUMAN (79-437): 9.96e-25: 110: 13.90		CHD3_HUMAN (270-1647): 0: 733: 21.04
+	Hs
		1086762 BPTF_HUMAN (29-421): 8.88e-25: 110: 13.28		CHD4_HUMAN (394-1632): 0: 726: 21.98
+	Hs
		1086794 BPTF_HUMAN (29-421): 8.88e-25: 110: 13.28		CHD5_HUMAN (416-1638): 0: 720: 22.44