HitPredict

Interactor 1: CREST (O75177)
Calcium-responsive transactivator (SS18-like protein 1) (SYT homolog 1)
Gene: SS18L1

Interactor 2: SSXT (Q15532)
Protein SSXT (Protein SYT) (Synovial sarcoma translocated to X chromosome protein)
Gene: SS18

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SSXT~SSXT
Common GO terms	GO:0003713 - transcription coactivator activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 396 Hs			1 418
+	Hs
		1149725 SSXT_HUMAN (1-396): 5.48e-68: 222: 53.83		SSXT_HUMAN (1-418): 1.23e-79: 253: 100.00
+	Hs
		1196853 Q4VAX2_HUMAN (1-396): 1.87e-67: 221: 53.59		Q4VAX2_HUMAN (1-418): 3.34e-79: 252: 99.76
+	Hs
		273961 CREST_HUMAN (1-396): 3.17e-78: 248: 100.00		CREST_HUMAN (1-418): 2.7e-58: 197: 55.26
+	Hs
		273985 CREST_HUMAN (1-396): 3.17e-78: 248: 100.00		SMCA2_HUMAN (70-418): 1.68e-31: 129: 19.16
+	Mm
		1231593 SMCA2_MOUSE (74-384): 6.61e-36: 142: 17.93		CREST_MOUSE (1-418): 3.75e-63: 210: 57.66
+	Hs
		903165 SSXT_HUMAN (1-396): 5.48e-68: 222: 53.83		SMCA2_HUMAN (70-418): 1.68e-31: 129: 19.16
+	Hs
		273986 CREST_HUMAN (1-396): 3.17e-78: 248: 100.00		SMCA4_HUMAN (78-418): 1.86e-20: 96.3: 16.81
+	Mm
		1189457 CREST_MOUSE (1-396): 4.66e-78: 248: 89.80		SMCA4_MOUSE (70-418): 2.4e-19: 92.8: 16.11
+	Mm
		1189442 SSXT_MOUSE (1-396): 7.29e-71: 230: 56.22		SMCA4_MOUSE (70-418): 2.4e-19: 92.8: 16.11
+	Rn
		93310 D4ABC5_RAT (1-396): 7.25e-70: 227: 56.22		SMCA4_RAT (70-418): 2.68e-19: 92.8: 16.39
+	Hs
		903372 SSXT_HUMAN (1-396): 5.48e-68: 222: 53.83		SMCA4_HUMAN (78-418): 1.86e-20: 96.3: 16.81
+	Hs
		62704 A4PIW0_HUMAN (1-342): 3.8e-54: 187: 47.65		SMCA2_HUMAN (70-418): 1.68e-31: 129: 19.16
+	Hs
		62693 A4PIV7_HUMAN (1-388): 2.75e-63: 212: 52.93		SMCA4_HUMAN (78-418): 1.86e-20: 96.3: 16.81
+	Hs
		62700 A4PIV9_HUMAN (1-388): 2.69e-63: 212: 52.93		SMCA4_HUMAN (78-418): 1.86e-20: 96.3: 16.81
+	Hs
		903274 S18L2_HUMAN (1-73): 9.9e-40: 137: 60.27		SMCA2_HUMAN (70-418): 1.68e-31: 129: 19.16
+	Mm
		1189445 SMCA2_MOUSE (74-384): 6.61e-36: 142: 17.93		SMCA4_MOUSE (70-418): 2.4e-19: 92.8: 16.11
+	Hs
		903511 S18L2_HUMAN (1-73): 9.9e-40: 137: 60.27		SMCA4_HUMAN (78-418): 1.86e-20: 96.3: 16.81
+	Hs
		903105 SMCA2_HUMAN (74-384): 1.05e-26: 114: 15.67		SMCA4_HUMAN (78-418): 1.86e-20: 96.3: 16.81