HitPredict

Interactor 1: FLNB (O75369)
Filamin-B (FLN-B) (ABP-278) (ABP-280 homolog) (Actin-binding-like protein) (Beta-filamin) (Filamin homolog 1) (Fh1) (Filamin-3) (Thyroid autoantigen) (Truncated actin-binding protein) (Truncated ABP)
Gene: FLNB

Interactor 2: CDK9 (P50750)
Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division cycle 2-like protein kinase 4) (Cell division protein kinase 9) (Serine/threonine-protein kinase PITALRE) (Tat-associated kinase complex catalytic subunit)
Gene: CDK9

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26209609
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 2602 Hs			1 372
+	Hs
		278018 FLNB_HUMAN (1-2602): 0: 2855: 100.00		CDK2_HUMAN (16-321): 3.19e-137: 394: 38.76
+	Hs
		637406 FLNA_HUMAN (1-2602): 0: 2661: 69.59		CDK9_HUMAN (1-372): 1.49e-148: 426: 100.00
+	Hs
		637351 FLNA_HUMAN (1-2602): 0: 2661: 69.59		CDK2_HUMAN (16-321): 3.19e-137: 394: 38.76
+	Hs
		443175 FLNA_HUMAN (1-2602): 0: 2661: 69.59		CDK1_HUMAN (16-315): 1.05e-123: 359: 40.40
+	Hs
		667847 FLNC_HUMAN (6-2602): 0: 1470: 35.38		CDK2_HUMAN (16-321): 3.19e-137: 394: 38.76
+	Hs
		555641 ACTN1_HUMAN (5-364): 3.9e-117: 397: 27.15		CDK9_HUMAN (1-372): 1.49e-148: 426: 100.00
+	Hs
		897746 SPTB2_HUMAN (6-367): 4.88e-108: 389: 28.65		CDK9_HUMAN (1-372): 1.49e-148: 426: 100.00
+	Hs
		224663 ACTN4_HUMAN (12-364): 1e-113: 388: 26.58		CDK9_HUMAN (1-372): 1.49e-148: 426: 100.00
+	Hs
		555606 ACTN1_HUMAN (5-364): 3.9e-117: 397: 27.15		CDK2_HUMAN (16-321): 3.19e-137: 394: 38.76
+	Hs
		224701 ACTN4_HUMAN (12-364): 1e-113: 388: 26.58		MK07_HUMAN (12-372): 2.67e-132: 399: 29.75
+	Rn
		73572 B2GVB3_RAT (5-364): 8.54e-119: 402: 27.15		MK03_RAT (9-362): 7.01e-132: 384: 30.79
+	Hs
		667784 SPTB2_HUMAN (6-367): 4.88e-108: 389: 28.65		CDK2_HUMAN (16-321): 3.19e-137: 394: 38.76
+	Rn
		640095 ACTN1_RAT (5-364): 2.3e-117: 398: 27.15		MK03_RAT (9-362): 7.01e-132: 384: 30.79
+	Rn
		92873 D3ZCV0_RAT (5-364): 1.69e-116: 395: 26.61		MK03_RAT (9-362): 7.01e-132: 384: 30.79
+	Hs
		540246 SPTB1_HUMAN (6-282): 2.13e-95: 347: 32.14		CDK9_HUMAN (1-372): 1.49e-148: 426: 100.00
+	Rn
		640087 ACTN4_RAT (12-364): 1.34e-113: 387: 26.58		MK03_RAT (9-362): 7.01e-132: 384: 30.79