HitPredict

Interactor 1: SC22B (O75396)
Vesicle-trafficking protein SEC22b (ER-Golgi SNARE of 24 kDa) (ERS-24) (ERS24) (SEC22 vesicle-trafficking protein homolog B) (SEC22 vesicle-trafficking protein-like 1)
Gene: SEC22B

Interactor 2: MIRO2 (Q8IXI1)
Mitochondrial Rho GTPase 2 (MIRO-2) (hMiro-2) (EC 3.6.5.-) (Ras homolog gene family member T2)
Gene: RHOT2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	32877691
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 215 Hs			1 618
+	Hs
		280113 SC22B_HUMAN (1-215): 1.35e-90: 266: 100.00		RAC2_HUMAN (3-183): 1.38e-79: 251: 27.69
+	Hs
		280171 SC22B_HUMAN (1-215): 1.35e-90: 266: 100.00		RAC3_HUMAN (3-168): 9.64e-79: 249: 27.22
+	Hs
		280172 SC22B_HUMAN (1-215): 1.35e-90: 266: 100.00		CDC42_HUMAN (3-172): 5.7e-77: 244: 25.54
+	Hs
		280208 SC22B_HUMAN (1-215): 1.35e-90: 266: 100.00		RAB35_HUMAN (5-168): 3.57e-76: 242: 24.70
+	Hs
		280184 SC22B_HUMAN (1-215): 1.35e-90: 266: 100.00		RHOG_HUMAN (3-170): 1.69e-74: 238: 27.47
+	Hs
		280180 SC22B_HUMAN (1-215): 1.35e-90: 266: 100.00		RAC1_HUMAN (3-181): 3.96e-74: 237: 26.43
+	Hs
		280177 SC22B_HUMAN (1-215): 1.35e-90: 266: 100.00		RB11A_HUMAN (5-202): 4.27e-72: 232: 19.00
+	Hs
		580942 VAMP7_HUMAN (31-198): 2.72e-62: 195: 22.62		RAC2_HUMAN (3-183): 1.38e-79: 251: 27.69
+	Hs
		907991 VAMP7_HUMAN (31-198): 2.72e-62: 195: 22.62		RAC3_HUMAN (3-168): 9.64e-79: 249: 27.22
+	Hs
		907993 VAMP7_HUMAN (31-198): 2.72e-62: 195: 22.62		CDC42_HUMAN (3-172): 5.7e-77: 244: 25.54
+	Sc
		376268 SEC22_YEAST (1-215): 3.09e-66: 204: 35.65		YPT1_YEAST (5-184): 5.56e-71: 229: 18.68
+	Hs
		280178 SC22B_HUMAN (1-215): 1.35e-90: 266: 100.00		RHOB_HUMAN (6-168): 4.59e-13: 70.1: 29.38
+	Hs
		280174 SC22B_HUMAN (1-215): 1.35e-90: 266: 100.00		RHOA_HUMAN (6-168): 1.75e-11: 65.5: 28.25
+	Hs
		280343 SC22B_HUMAN (1-215): 1.35e-90: 266: 100.00		RHOF_HUMAN (2-167): 3.39e-11: 65.1: 26.67
+	Hs
		280099 SC22B_HUMAN (1-215): 1.35e-90: 266: 100.00		RHOC_HUMAN (6-168): 3.88e-11: 64.3: 28.25
+	Hs
		126399 SC22B_HUMAN (1-215): 1.35e-90: 266: 100.00		RHOD_HUMAN (3-167): 1.27e-10: 63.2: 28.89
+	Hs
		907996 VAMP7_HUMAN (31-198): 2.72e-62: 195: 22.62		RHOA_HUMAN (6-168): 1.75e-11: 65.5: 28.25
+	Hs
		466163 VAMP7_HUMAN (31-198): 2.72e-62: 195: 22.62		RHOC_HUMAN (6-168): 3.88e-11: 64.3: 28.25
+	Hs
		126517 VAMP7_HUMAN (31-198): 2.72e-62: 195: 22.62		RHOD_HUMAN (3-167): 1.27e-10: 63.2: 28.89
+	Hs
		601216 VAMP7_HUMAN (31-198): 2.72e-62: 195: 22.62		RHOQ_HUMAN (5-169): 2.03e-10: 62.8: 26.26