HitPredict

Interactor 1: SC22B (O75396)
Vesicle-trafficking protein SEC22b (ER-Golgi SNARE of 24 kDa) (ERS-24) (ERS24) (SEC22 vesicle-trafficking protein homolog B) (SEC22 vesicle-trafficking protein-like 1)
Gene: SEC22B

Interactor 2: BET1L (Q9NYM9)
BET1-like protein (Golgi SNARE with a size of 15 kDa) (GOS-15) (GS15) (Vesicle transport protein GOS15)
Gene: BET1L

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000139 - Golgi membrane GO:0005484 - SNAP receptor activity GO:0015031 - protein transport
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 215 Hs			1 111
+	Hs
		179768 SC22B_HUMAN (1-215): 1.35e-90: 266: 100.00		BET1_HUMAN (2-106): 3.69e-36: 120: 31.43
+	Hs
		249804 SC22B_HUMAN (1-215): 1.35e-90: 266: 100.00		STX10_HUMAN (7-91): 6.1e-25: 95.9: 12.94
+	Hs
		225883 SC22B_HUMAN (1-215): 1.35e-90: 266: 100.00		STX6_HUMAN (2-91): 2.25e-21: 86.6: 15.56
+	Dm
		305598 O77434_DROME (1-215): 1.02e-77: 233: 56.74		Q9VVX6_DROME (29-106): 1.22e-24: 91.6: 30.77
+	Dm
		121833 M9PGI6_DROME (1-215): 5.4e-76: 229: 56.22		Q9VVX6_DROME (29-106): 1.22e-24: 91.6: 30.77
+	Hs
		179853 VAMP7_HUMAN (31-198): 2.72e-62: 195: 22.62		BET1_HUMAN (2-106): 3.69e-36: 120: 31.43
+	Sc
		646213 SEC22_YEAST (1-215): 3.09e-66: 204: 35.65		BET1_YEAST (1-105): 3.83e-26: 96.2: 16.19
+	Dm
		1263475 Q7JYX5_DROME (30-214): 6.09e-64: 199: 20.54		Q9VVX6_DROME (29-106): 1.22e-24: 91.6: 30.77
+	Rn
		1204259 YKT6_RAT (30-188): 8.92e-53: 170: 23.13		BET1_RAT (2-106): 4.25e-36: 120: 31.43
+	Hs
		179756 YKT6_HUMAN (30-188): 3.42e-53: 170: 23.13		BET1_HUMAN (2-106): 3.69e-36: 120: 31.43
+	Mm
		205242 YKT6_MOUSE (30-188): 1.35e-52: 169: 23.13		BET1_MOUSE (2-106): 1.13e-35: 119: 31.43
+	Hs
		192330 YKT6_HUMAN (30-188): 3.42e-53: 170: 23.13		BET1L_HUMAN (1-111): 7.16e-35: 117: 100.00
+	Rn
		204384 YKT6_RAT (30-188): 8.92e-53: 170: 23.13		BET1L_RAT (1-111): 5.81e-33: 112: 88.29
+	Hs
		225968 VAMP7_HUMAN (31-198): 2.72e-62: 195: 22.62		STX6_HUMAN (2-91): 2.25e-21: 86.6: 15.56
+	Hs
		192145 YKT6_HUMAN (30-188): 3.42e-53: 170: 23.13		STX6_HUMAN (2-91): 2.25e-21: 86.6: 15.56
+	Sc
		652917 YKT6_YEAST (31-188): 1.81e-44: 148: 24.54		BET1_YEAST (1-105): 3.83e-26: 96.2: 16.19
+	Dm
		1487522 Q9W3M8_DROME (28-188): 3.54e-45: 150: 20.25		Q9VVX6_DROME (29-106): 1.22e-24: 91.6: 30.77