HitPredict

Interactor 1: TACC1 (O75410)
Transforming acidic coiled-coil-containing protein 1 (Gastric cancer antigen Ga55) (Taxin-1)
Gene: TACC1

Interactor 2: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005813 - centrosome GO:0005829 - cytosol GO:0007097 - nuclear migration GO:0016020 - membrane and 1 others more... GO:0030496 - midbody
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 805 Hs			1 191
+	Hs
		281032 TACC1_HUMAN (1-805): 1.58e-108: 352: 100.00		RHOG_HUMAN (1-191): 7.33e-80: 237: 60.73
+	Hs
		281025 TACC1_HUMAN (1-805): 1.58e-108: 352: 100.00		RHOA_HUMAN (5-191): 2.51e-78: 233: 53.48
+	Hs
		280996 TACC1_HUMAN (1-805): 1.58e-108: 352: 100.00		RAC2_HUMAN (1-191): 1.01e-77: 232: 68.75
+	Hs
		280989 TACC1_HUMAN (1-805): 1.58e-108: 352: 100.00		RHOC_HUMAN (5-191): 3.38e-76: 228: 52.41
+	Hs
		281023 TACC1_HUMAN (1-805): 1.58e-108: 352: 100.00		RAC3_HUMAN (1-177): 7.58e-76: 227: 72.32
+	Hs
		953777 CRBG1_HUMAN (16-618): 3.73e-37: 153: 15.58		RAC3_HUMAN (1-177): 7.58e-76: 227: 72.32
+	Hs
		601347 MICA3_HUMAN (2-777): 1.48e-21: 103: 10.80		RHOQ_HUMAN (4-187): 7.38e-91: 266: 67.94
+	Hs
		1273864 MICA3_HUMAN (2-777): 1.48e-21: 103: 10.80		RHOJ_HUMAN (2-188): 2.68e-85: 252: 64.17
+	Hs
		988487 HUWE1_HUMAN (166-500): 1.87e-23: 109: 12.30		RAC1_HUMAN (1-191): 1.15e-81: 242: 70.31
+	Hs
		955331 HUWE1_HUMAN (166-500): 1.87e-23: 109: 12.30		CDC42_HUMAN (1-191): 9.95e-80: 237: 100.00
+	Hs
		988477 MICA3_HUMAN (2-777): 1.48e-21: 103: 10.80		RAC1_HUMAN (1-191): 1.15e-81: 242: 70.31
+	Hs
		319077 K0754_HUMAN (4-261): 2.09e-16: 86.6: 11.99		RHOJ_HUMAN (2-188): 2.68e-85: 252: 64.17
+	Hs
		953526 MICA3_HUMAN (2-777): 1.48e-21: 103: 10.80		RAC3_HUMAN (1-177): 7.58e-76: 227: 72.32
+	Hs
		319060 K0754_HUMAN (4-261): 2.09e-16: 86.6: 11.99		RAC1_HUMAN (1-191): 1.15e-81: 242: 70.31
+	Hs
		319064 K0754_HUMAN (4-261): 2.09e-16: 86.6: 11.99		RHOG_HUMAN (1-191): 7.33e-80: 237: 60.73
+	Hs
		319057 K0754_HUMAN (4-261): 2.09e-16: 86.6: 11.99		RHOA_HUMAN (5-191): 2.51e-78: 233: 53.48
+	Hs
		319049 K0754_HUMAN (4-261): 2.09e-16: 86.6: 11.99		RAC2_HUMAN (1-191): 1.01e-77: 232: 68.75
+	Hs
		319046 K0754_HUMAN (4-261): 2.09e-16: 86.6: 11.99		RHOC_HUMAN (5-191): 3.38e-76: 228: 52.41
+	Hs
		319056 K0754_HUMAN (4-261): 2.09e-16: 86.6: 11.99		RAC3_HUMAN (1-177): 7.58e-76: 227: 72.32
+	Hs
		319071 K0754_HUMAN (4-261): 2.09e-16: 86.6: 11.99		RHOU_HUMAN (4-186): 1.03e-72: 221: 58.82