HitPredict

Interactor 1: CIAO1 (O76071)
Probable cytosolic iron-sulfur protein assembly protein CIAO1 (WD repeat-containing protein 39)
Gene: CIAO1

Interactor 2: TCPH (Q99832)
T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta) (Chaperonin containing T-complex polypeptide 1 subunit 7) (HIV-1 Nef-interacting protein) [Cleaved into: T-complex protein 1 subunit eta, N-terminally processed]
Gene: CCT7

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 339 Hs			1 543
+	Hs
		282850 CIAO1_HUMAN (1-337): 6.29e-105: 312: 100.00		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		282848 CIAO1_HUMAN (1-337): 6.29e-105: 312: 100.00		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		282815 CIAO1_HUMAN (1-337): 6.29e-105: 312: 100.00		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		826784 POC1B_HUMAN (92-339): 1.04e-59: 200: 20.97		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		821326 POC1B_HUMAN (92-339): 1.04e-59: 200: 20.97		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		573384 POC1B_HUMAN (92-339): 1.04e-59: 200: 20.97		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		826807 FBXW7_HUMAN (3-217): 6.6e-46: 167: 19.73		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		1306704 NLE1_HUMAN (226-339): 2.65e-18: 87.5: 14.91		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Sc
		744637 TAF5_YEAST (124-339): 2.22e-35: 138: 19.48		TCPH_YEAST (2-542): 0: 587: 62.45
+	Hs
		573406 FBXW7_HUMAN (3-217): 6.6e-46: 167: 19.73		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Sc
		744632 TAF5_YEAST (124-339): 2.22e-35: 138: 19.48		TCPE_YEAST (2-526): 0: 568: 29.98
+	Sc
		744617 TAF5_YEAST (124-339): 2.22e-35: 138: 19.48		TCPG_YEAST (2-527): 0: 546: 30.68
+	Hs
		826601 WDR5_HUMAN (225-339): 4.64e-18: 85.5: 15.65		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		821437 NLE1_HUMAN (226-339): 2.65e-18: 87.5: 14.91		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		821139 SEC13_HUMAN (28-281): 8.06e-19: 87.4: 29.64		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		821152 WDR5_HUMAN (225-339): 4.64e-18: 85.5: 15.65		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		573201 WDR5_HUMAN (225-339): 4.64e-18: 85.5: 15.65		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		843299 POC1B_HUMAN (92-339): 1.04e-59: 200: 20.97		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79
+	Dm
		186253 GBLP_DROME (92-339): 5.66e-46: 160: 18.50		Q9W392_DROME (1-527): 6.53e-90: 288: 36.21
+	Hs
		843411 NLE1_HUMAN (226-339): 2.65e-18: 87.5: 14.91		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79