HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: TTK (P33981)
Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein kinase) (PYT)
Gene: TTK

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.55	0.60	0.578

Property	Details
Experiments	19332559
Identification Methods	affinity chromatography technology, pull down, enzymatic study
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 857
+	Hs
		386767 P53_HUMAN (1-393): 0: 619: 100.00		KPCD1_HUMAN (176-857): 3.37e-133: 421: 15.27
+	Hs
		296502 P53_HUMAN (1-393): 0: 619: 100.00		KPCD3_HUMAN (174-853): 3.32e-129: 411: 15.32
+	Hs
		387644 P53_HUMAN (1-393): 0: 619: 100.00		PAK5_HUMAN (178-798): 8.17e-116: 370: 15.37
+	Hs
		386351 P53_HUMAN (1-393): 0: 619: 100.00		KS6A3_HUMAN (477-818): 6.94e-81: 277: 21.05
+	Hs
		386780 P53_HUMAN (1-393): 0: 619: 100.00		KS6A2_HUMAN (525-818): 6.21e-81: 277: 22.29
+	Hs
		386785 P53_HUMAN (1-393): 0: 619: 100.00		KS6A1_HUMAN (477-790): 7.04e-77: 266: 21.96
+	Hs
		386943 P53_HUMAN (1-393): 0: 619: 100.00		ULK3_HUMAN (525-797): 3.59e-27: 117: 28.72
+	Hs
		387513 P53_HUMAN (1-393): 0: 619: 100.00		PLK3_HUMAN (522-790): 4.2e-20: 97.4: 27.80
+	Hs
		386533 P53_HUMAN (1-393): 0: 619: 100.00		CDK5_HUMAN (525-790): 5.66e-20: 93.2: 27.70