HitPredict

Interactor 1: EED (O75530)
Polycomb protein EED (hEED) (Embryonic ectoderm development protein) (WD protein associating with integrin cytoplasmic tails 1) (WAIT-1)
Gene: EED

Interactor 2: DX39B (Q13838)
Spliceosome RNA helicase DDX39B (EC 3.6.4.13) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (DEAD box protein UAP56) (HLA-B-associated transcript 1 protein)
Gene: DDX39B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24457600
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Helicase_C~WD40
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 441 Hs			1 428
+	Mm
		1223843 EED_MOUSE (1-441): 1.63e-90: 283: 100.00		DDX3X_MOUSE (3-423): 2.05e-152: 448: 28.06
+	Mm
		1297361 EED_MOUSE (1-441): 1.63e-90: 283: 100.00		Q8BTS0_MOUSE (6-421): 6.03e-136: 404: 25.24
+	Hs
		285069 EED_HUMAN (1-441): 1.63e-90: 283: 100.00		DDX5_HUMAN (6-421): 6.66e-136: 404: 25.00
+	Hs
		285396 EED_HUMAN (1-441): 1.63e-90: 283: 100.00		DDX17_HUMAN (6-423): 2.63e-134: 404: 25.06
+	Mm
		1197468 EED_MOUSE (1-441): 1.63e-90: 283: 100.00		DDX17_MOUSE (6-423): 5.8e-135: 403: 25.06
+	Mm
		1362845 EED_MOUSE (1-441): 1.63e-90: 283: 100.00		DX39B_MOUSE (1-428): 1.58e-137: 402: 99.53
+	Mm
		1354008 EED_MOUSE (1-441): 1.63e-90: 283: 100.00		DX39A_MOUSE (1-428): 1.74e-132: 389: 90.42
+	Hs
		123018 EED_HUMAN (1-441): 1.63e-90: 283: 100.00		DX39A_HUMAN (1-428): 5.47e-131: 385: 89.95
+	Hs
		141231 EED_HUMAN (1-441): 1.63e-90: 283: 100.00		DDX3X_HUMAN (3-423): 9.22e-126: 380: 27.84
+	Hs
		193129 POC1A_HUMAN (230-440): 1.55e-37: 142: 14.54		DDX3Y_HUMAN (2-423): 4.14e-153: 450: 28.44
+	Mm
		1362196 EED_MOUSE (1-441): 1.63e-90: 283: 100.00		IF4A3_MOUSE (52-415): 1.05e-80: 256: 38.36
+	Hs
		285121 EED_HUMAN (1-441): 1.63e-90: 283: 100.00		IF4A3_HUMAN (52-415): 7.93e-81: 256: 38.36
+	Hs
		285087 EED_HUMAN (1-441): 1.63e-90: 283: 100.00		DDX6_HUMAN (30-426): 2.51e-75: 244: 35.68
+	Mm
		932551 EED_MOUSE (1-441): 1.63e-90: 283: 100.00		DDX6_MOUSE (30-426): 1.75e-75: 244: 35.68
+	Hs
		1369337 FBXW7_HUMAN (219-439): 2.95e-26: 113: 15.32		DDX17_HUMAN (6-423): 2.63e-134: 404: 25.06
+	Hs
		1369406 NLE1_HUMAN (296-440): 9.08e-25: 108: 16.45		DDX17_HUMAN (6-423): 2.63e-134: 404: 25.06
+	Hs
		608695 SNR40_HUMAN (298-441): 2.31e-21: 96.6: 14.29		DDX5_HUMAN (6-421): 6.66e-136: 404: 25.00
+	Hs
		123157 FBXW7_HUMAN (219-439): 2.95e-26: 113: 15.32		DX39A_HUMAN (1-428): 5.47e-131: 385: 89.95
+	Hs
		141604 FBXW7_HUMAN (219-439): 2.95e-26: 113: 15.32		DDX3X_HUMAN (3-423): 9.22e-126: 380: 27.84
+	Sc
		812093 COPA_YEAST (9-295): 5.36e-29: 122: 11.15		DHH1_YEAST (47-426): 4.52e-79: 254: 38.32