HitPredict

Interactor 1: EED (O75530)
Polycomb protein EED (hEED) (Embryonic ectoderm development protein) (WD protein associating with integrin cytoplasmic tails 1) (WAIT-1)
Gene: EED

Interactor 2: DDX50 (Q9BQ39)
ATP-dependent RNA helicase DDX50 (EC 3.6.4.13) (DEAD box protein 50) (Gu-beta) (Nucleolar protein Gu2)
Gene: DDX50

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	24457600
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Helicase_C~WD40
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 441 Hs			1 737
+	Mm
		1362605 EED_MOUSE (1-441): 1.63e-90: 283: 100.00		DDX50_MOUSE (1-737): 1.56e-171: 512: 95.12
+	Mm
		1362558 EED_MOUSE (1-441): 1.63e-90: 283: 100.00		DDX27_MOUSE (30-577): 2.8e-154: 468: 28.70
+	Hs
		285487 EED_HUMAN (1-441): 1.63e-90: 283: 100.00		DDX21_HUMAN (20-736): 8.65e-147: 449: 59.86
+	Mm
		1362762 EED_MOUSE (1-441): 1.63e-90: 283: 100.00		DDX21_MOUSE (17-736): 1.95e-145: 448: 56.31
+	Hs
		285396 EED_HUMAN (1-441): 1.63e-90: 283: 100.00		DDX17_HUMAN (74-587): 2.52e-140: 431: 24.86
+	Mm
		1197468 EED_MOUSE (1-441): 1.63e-90: 283: 100.00		DDX17_MOUSE (74-585): 1.97e-139: 426: 24.95
+	Mm
		1297361 EED_MOUSE (1-441): 1.63e-90: 283: 100.00		Q8BTS0_MOUSE (73-561): 6.16e-140: 426: 25.25
+	Hs
		285069 EED_HUMAN (1-441): 1.63e-90: 283: 100.00		DDX5_HUMAN (73-588): 8.52e-140: 426: 24.90
+	Mm
		1283488 EED_MOUSE (1-441): 1.63e-90: 283: 100.00		DDX42_MOUSE (13-732): 4.36e-135: 423: 21.53
+	Hs
		285349 EED_HUMAN (1-441): 1.63e-90: 283: 100.00		DDX42_HUMAN (13-732): 1.92e-132: 417: 20.96
+	Hs
		141231 EED_HUMAN (1-441): 1.63e-90: 283: 100.00		DDX3X_HUMAN (15-527): 6.57e-134: 412: 24.24
+	Mm
		1223843 EED_MOUSE (1-441): 1.63e-90: 283: 100.00		DDX3X_MOUSE (15-527): 1.59e-132: 408: 23.86
+	Hs
		1380188 FBXW7_HUMAN (219-439): 2.95e-26: 113: 15.32		DDX21_HUMAN (20-736): 8.65e-147: 449: 59.86
+	Hs
		193129 POC1A_HUMAN (230-440): 1.55e-37: 142: 14.54		DDX3Y_HUMAN (15-528): 4.46e-131: 405: 23.82
+	Hs
		1369337 FBXW7_HUMAN (219-439): 2.95e-26: 113: 15.32		DDX17_HUMAN (74-587): 2.52e-140: 431: 24.86
+	Hs
		1369406 NLE1_HUMAN (296-440): 9.08e-25: 108: 16.45		DDX17_HUMAN (74-587): 2.52e-140: 431: 24.86
+	Hs
		1369343 SNR40_HUMAN (298-441): 2.31e-21: 96.6: 14.29		DDX17_HUMAN (74-587): 2.52e-140: 431: 24.86
+	Hs
		141604 FBXW7_HUMAN (219-439): 2.95e-26: 113: 15.32		DDX3X_HUMAN (15-527): 6.57e-134: 412: 24.24
+	Hs
		608695 SNR40_HUMAN (298-441): 2.31e-21: 96.6: 14.29		DDX5_HUMAN (73-588): 8.52e-140: 426: 24.90
+	Sc
		444583 COPA_YEAST (9-295): 5.36e-29: 122: 11.15		DED1_YEAST (139-492): 8.56e-56: 203: 35.87