HitPredict

Interactor 1: RECQ4 (O94761)
ATP-dependent DNA helicase Q4 (EC 5.6.2.4) (DNA 3'-5' helicase RecQ4) (DNA helicase, RecQ-like type 4) (RecQ4) (RTS) (RecQ protein-like 4)
Gene: RECQL4

Interactor 2: EIF3I (Q13347)
Eukaryotic translation initiation factor 3 subunit I (eIF3i) (Eukaryotic translation initiation factor 3 subunit 2) (TGF-beta receptor-interacting protein 1) (TRIP-1) (eIF-3-beta) (eIF3 p36)
Gene: EIF3I

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	29229926
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ANAPC4_WD40~DEAD
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1208 Hs			1 325
+	Hs
		196928 RECQ4_HUMAN (1-1208): 0: 794: 100.00		PRP4_HUMAN (95-325): 1.03e-46: 166: 11.67
+	Hs
		294619 RECQ4_HUMAN (1-1208): 0: 794: 100.00		WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65
+	Hs
		294989 RECQ4_HUMAN (1-1208): 0: 794: 100.00		WDR5B_HUMAN (180-325): 2.45e-34: 129: 13.61
+	Hs
		295445 RECQ4_HUMAN (1-1208): 0: 794: 100.00		STRAP_HUMAN (186-316): 4.07e-09: 58.9: 20.15
+	Hs
		134019 DDX3X_HUMAN (291-843): 4.68e-127: 407: 14.85		EIF3I_HUMAN (1-325): 3.67e-93: 281: 100.00
+	Hs
		181721 DDX3Y_HUMAN (305-843): 2.04e-126: 405: 15.09		POC1A_HUMAN (81-324): 1.17e-56: 190: 14.63
+	Hs
		867630 BLM_HUMAN (474-836): 1.6e-132: 441: 33.42		SNR40_HUMAN (3-122): 1.87e-26: 108: 20.93
+	Hs
		133956 DDX3X_HUMAN (291-843): 4.68e-127: 407: 14.85		WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65
+	Hs
		903507 DDX47_HUMAN (439-879): 2.35e-121: 384: 18.32		WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65
+	Hs
		903410 DDX17_HUMAN (306-903): 3.02e-117: 383: 17.50		WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65
+	Hs
		571382 DDX5_HUMAN (374-903): 1.45e-115: 374: 16.18		WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65
+	Hs
		1288310 DDX31_HUMAN (197-1041): 1.14e-123: 404: 16.37		SNR40_HUMAN (3-122): 1.87e-26: 108: 20.93
+	Hs
		867626 BLM_HUMAN (474-836): 1.6e-132: 441: 33.42		FBXW7_HUMAN (5-75): 4.23e-09: 59.6: 24.05
+	Hs
		295548 RECQ5_HUMAN (463-846): 3.99e-118: 392: 32.45		SNR40_HUMAN (3-122): 1.87e-26: 108: 20.93
+	Hs
		1271621 DDX17_HUMAN (306-903): 3.02e-117: 383: 17.50		SNR40_HUMAN (3-122): 1.87e-26: 108: 20.93
+	Hs
		1050616 WRN_HUMAN (465-856): 8.98e-111: 381: 29.28		SNR40_HUMAN (3-122): 1.87e-26: 108: 20.93
+	Hs
		571547 DDX5_HUMAN (374-903): 1.45e-115: 374: 16.18		SNR40_HUMAN (3-122): 1.87e-26: 108: 20.93
+	Hs
		134154 DDX3X_HUMAN (291-843): 4.68e-127: 407: 14.85		FBXW7_HUMAN (5-75): 4.23e-09: 59.6: 24.05
+	Hs
		134258 DDX3X_HUMAN (291-843): 4.68e-127: 407: 14.85		STRAP_HUMAN (186-316): 4.07e-09: 58.9: 20.15
+	Hs
		1271615 DDX17_HUMAN (306-903): 3.02e-117: 383: 17.50		FBXW7_HUMAN (5-75): 4.23e-09: 59.6: 24.05