HitPredict

Interactor 1: STAM2 (O75886)
Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein)
Gene: STAM2

Interactor 2: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.95	1.00	0.977

Property	Details
Experiments	20504764, 28190767, 31699778, 31494268, 18626516, 38803224, 26601948, 27725184, 40437099, 21121635, 22841719, 12750381
Identification Methods	pull down, unspecified method, x-ray crystallography, cross-linking study, surface plasmon resonance
Interaction Type	direct interaction, association, physical association

Property	Details
Interacting Pfam domains	SH3_1~ubiquitin, UIM~ubiquitin, VHS~ubiquitin
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 525 Hs			1 685
+	Hs
		508369 STAM1_HUMAN (1-510): 4.16e-112: 345: 54.88		UBC_HUMAN (1-685): 0: 857: 100.00
+	Hs
		508173 TM1L2_HUMAN (1-466): 1.87e-87: 280: 17.19		UBC_HUMAN (1-685): 0: 857: 100.00
+	Rn
		81583 B5DF55_RAT (1-513): 4.44e-113: 347: 54.25		UBC_RAT (1-637): 0: 779: 98.90
+	Hs
		256434 TOM1_HUMAN (1-444): 8.1e-81: 262: 17.68		UBC_HUMAN (1-685): 0: 857: 100.00
+	Hs
		290232 TM1L1_HUMAN (6-494): 1.97e-65: 221: 15.62		UBC_HUMAN (1-685): 0: 857: 100.00
+	Hs
		508803 GGA1_HUMAN (2-516): 2.51e-62: 217: 14.50		UBC_HUMAN (1-685): 0: 857: 100.00
+	Rn
		591440 SPTN1_RAT (103-481): 1.05e-55: 204: 14.35		UBC_RAT (1-637): 0: 779: 98.90
+	Bt
		509943 Q58CQ6_BOVIN (2-422): 8.25e-64: 216: 13.43		UBC_BOVIN (1-461): 0: 579: 98.92
+	Sc
		509585 VPS27_YEAST (1-488): 9.24e-59: 207: 16.02		UBI4P_YEAST (381-685): 4.09e-126: 380: 95.74
+	Hs
		296483 STAM2_HUMAN (1-525): 1.05e-141: 420: 100.00		RS27A_HUMAN (609-684): 7.26e-41: 148: 100.00
+	Hs
		296425 STAM2_HUMAN (1-525): 1.05e-141: 420: 100.00		UBB_HUMAN (1-77): 1.15e-26: 110: 98.70
+	Mm
		313050 STAM2_MOUSE (1-525): 1.57e-132: 396: 85.14		UBC_MOUSE (1-108): 2.12e-30: 129: 90.74
+	Ce
		144704 STAM1_CAEEL (4-395): 1.48e-65: 221: 27.03		UBIQ1_CAEEL (1-230): 9.64e-87: 291: 97.83
+	Hs
		987143 STAM1_HUMAN (1-510): 4.16e-112: 345: 54.88		RS27A_HUMAN (609-684): 7.26e-41: 148: 100.00
+	Mm
		509025 STAM1_MOUSE (1-513): 2.67e-115: 353: 53.96		UBC_MOUSE (1-108): 2.12e-30: 129: 90.74
+	Mm
		509080 TM1L2_MOUSE (1-466): 3.32e-87: 279: 17.79		UBC_MOUSE (1-108): 2.12e-30: 129: 90.74
+	Mm
		312915 TOM1_MOUSE (1-465): 1.7e-83: 269: 17.10		UBC_MOUSE (1-108): 2.12e-30: 129: 90.74
+	Mm
		509190 GGA1_MOUSE (2-516): 3.94e-64: 221: 13.74		UBC_MOUSE (1-108): 2.12e-30: 129: 90.74
+	Mm
		509153 GGA3_MOUSE (1-513): 1.96e-58: 208: 15.33		UBC_MOUSE (1-108): 2.12e-30: 129: 90.74
+	Hs
		507412 GGA1_HUMAN (2-516): 2.51e-62: 217: 14.50		UBB_HUMAN (1-77): 1.15e-26: 110: 98.70