HitPredict

Interactor 1: PHF14 (O94880)
PHD finger protein 14
Gene: PHF14

Interactor 2: H2AX (P16104)
Histone H2AX (H2a/x) (Histone H2A.X)
Gene: H2AX

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

Property	Details
Experiments	24981860, 28514442, 28242625, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0042393 - histone binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 948 Hs			1 143
+	Hs
		299027 PHF14_HUMAN (1-948): 0: 632: 100.00		H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70
+	Hs
		299030 PHF14_HUMAN (1-948): 0: 632: 100.00		H2A1_HUMAN (1-129): 7.56e-66: 197: 91.47
+	Hs
		299066 PHF14_HUMAN (1-948): 0: 632: 100.00		H2A2A_HUMAN (1-129): 7e-66: 197: 91.47
+	Hs
		260689 PHF14_HUMAN (1-948): 0: 632: 100.00		H2AY_HUMAN (1-142): 1.74e-61: 194: 60.69
+	Hs
		470306 BRPF1_HUMAN (104-712): 7.63e-105: 355: 17.73		H2A1_HUMAN (1-129): 7.56e-66: 197: 91.47
+	Hs
		319113 BRD1_HUMAN (167-711): 1.69e-90: 312: 18.07		H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00
+	Sc
		392604 NTO1_YEAST (162-679): 6.69e-91: 307: 18.38		H2A2_YEAST (16-124): 4.61e-53: 165: 82.57
+	Hs
		217435 AIRE_HUMAN (691-918): 3.69e-59: 214: 23.65		H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00
+	Hs
		217498 AIRE_HUMAN (691-918): 3.69e-59: 214: 23.65		H2A1C_HUMAN (1-129): 5.04e-66: 198: 92.25