Interactor 1: PRX1 (P34227)
Peroxiredoxin PRX1, mitochondrial (Prx) (EC 1.11.1.25) (EC 1.11.1.27) (1-Cys PRX) (Glutaredoxin-dependent peroxiredoxin) (Glutathione-dependent peroxiredoxin) (Mitochondrial thiol peroxidase) (mTPx) (Thioredoxin peroxidase)
Gene: PRX1

Interactor 2: PRX1 (P34227)
Peroxiredoxin PRX1, mitochondrial (Prx) (EC 1.11.1.25) (EC 1.11.1.27) (1-Cys PRX) (Glutaredoxin-dependent peroxiredoxin) (Glutathione-dependent peroxiredoxin) (Mitochondrial thiol peroxidase) (mTPx) (Thioredoxin peroxidase)
Gene: PRX1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.862

The method score is based on:

Property Details
Experiments 26159064, 32805320, 18552404
Identification Methods pull down, x-ray crystallography
Interaction Type direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains 1-cysPrx_C~1-cysPrx_C, 1-cysPrx_C~AhpC-TSA, AhpC-TSA~AhpC-TSA
Common GO terms GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0008379 - thioredoxin peroxidase activity
GO:0034599 - cellular response to oxidative stress
GO:0045454 - cell redox homeostasis
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 261
Sc

1 261
+ Bt
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ At
+ Hs
+ Mm

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Last updated: 15 Jul 2024