HitPredict

Interactor 1: FARP2 (O94887)
FERM, ARHGEF and pleckstrin domain-containing protein 2 (FERM domain-including RhoGEF) (FIR) (FERM, RhoGEF and pleckstrin domain-containing protein 2) (Pleckstrin homology domain-containing family C member 3) (PH domain-containing family C member 3)
Gene: FARP2

Interactor 2: ICLN (P54105)
Methylosome subunit pICln (Chloride channel, nucleotide sensitive 1A) (Chloride conductance regulatory protein ICln) (I(Cln)) (Chloride ion current inducer protein) (ClCI) (Reticulocyte pICln)
Gene: CLNS1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.675

Property	Details
Experiments	28514442, 33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005856 - cytoskeleton
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1054 Hs			1 237
+	Hs
		505591 EPB41_HUMAN (3-548): 2.87e-117: 383: 28.10		ICLN_HUMAN (1-237): 2.09e-113: 326: 100.00
+	Hs
		867467 E41L1_HUMAN (4-539): 4.5e-116: 381: 27.89		ICLN_HUMAN (1-237): 2.09e-113: 326: 100.00
+	Hs
		867491 E41L3_HUMAN (39-589): 1.93e-114: 381: 29.19		ICLN_HUMAN (1-237): 2.09e-113: 326: 100.00
+	Hs
		204636 E41L2_HUMAN (5-512): 5.21e-112: 373: 28.63		ICLN_HUMAN (1-237): 2.09e-113: 326: 100.00
+	Hs
		867438 FRMD7_HUMAN (44-552): 9.3e-107: 351: 38.93		ICLN_HUMAN (1-237): 2.09e-113: 326: 100.00
+	Hs
		640225 PTN3_HUMAN (25-508): 1.77e-100: 339: 25.00		ICLN_HUMAN (1-237): 2.09e-113: 326: 100.00