HitPredict

Interactor 1: PRP6 (O94906)
Pre-mRNA-processing factor 6 (Androgen receptor N-terminal domain-transactivating protein 1) (ANT-1) (PRP6 homolog) (U5 snRNP-associated 102 kDa protein) (U5-102 kDa protein)
Gene: PRPF6

Interactor 2: LMNA (P02545)
Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)]
Gene: LMNA

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.586

Property	Details
Experiments	25948554, 34133714
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016607 - nuclear speck
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 941 Hs			1 664
+	Hs
		300035 PRP6_HUMAN (1-941): 0: 610: 100.00		VIME_HUMAN (27-389): 3.94e-31: 129: 28.93
+	Hs
		360380 CRNL1_HUMAN (521-932): 8.54e-41: 164: 12.50		LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00
+	Hs
		359943 RRP5_HUMAN (474-761): 1.34e-26: 120: 14.09		LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00
+	Hs
		360054 CTR9_HUMAN (126-536): 3.3e-16: 85.7: 10.12		LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00
+	Hs
		595394 CRNL1_HUMAN (521-932): 8.54e-41: 164: 12.50		LMNB1_HUMAN (21-580): 5.16e-50: 185: 54.37
+	Hs
		174529 OGT1_HUMAN (120-352): 4.99e-10: 65.7: 11.39		LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00
+	Hs
		174563 OGT1_HUMAN (120-352): 4.99e-10: 65.7: 11.39		VIME_HUMAN (27-389): 3.94e-31: 129: 28.93