HitPredict

Interactor 1: GLSK (O94925)
Glutaminase kidney isoform, mitochondrial (GLS) (EC 3.5.1.2) (K-glutaminase) (L-glutamine amidohydrolase) [Cleaved into: Glutaminase kidney isoform, mitochondrial 68 kDa chain; Glutaminase kidney isoform, mitochondrial 65 kDa chain]
Gene: GLS

Interactor 2: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.58	1.00	0.768

Property	Details
Experiments	31478661, 31871319
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Ank_2~Ras
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 669 Hs			1 191
+	Hs
		300825 GLSK_HUMAN (1-669): 0: 849: 100.00		RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17
+	Hs
		300739 GLSK_HUMAN (1-669): 0: 849: 100.00		RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73
+	Hs
		300737 GLSK_HUMAN (1-669): 0: 849: 100.00		RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48
+	Hs
		300775 GLSK_HUMAN (1-669): 0: 849: 100.00		RHOU_HUMAN (4-186): 1.03e-72: 221: 58.82
+	Hs
		925238 ANK3_HUMAN (488-666): 4.57e-33: 139: 15.64		RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31
+	Hs
		893947 ANK3_HUMAN (488-666): 4.57e-33: 139: 15.64		CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00
+	Hs
		950953 ANK3_HUMAN (488-666): 4.57e-33: 139: 15.64		RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73
+	Hs
		900423 ANK3_HUMAN (488-666): 4.57e-33: 139: 15.64		RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48
+	Hs
		276162 PSD10_HUMAN (481-660): 5.42e-32: 125: 14.44		RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48
+	Hs
		925204 ANK2_HUMAN (540-669): 2.52e-25: 114: 21.54		RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31
+	Hs
		1021421 ANK3_HUMAN (488-666): 4.57e-33: 139: 15.64		RHOU_HUMAN (4-186): 1.03e-72: 221: 58.82
+	Hs
		564734 KDIS_HUMAN (455-623): 6.51e-16: 84.3: 13.45		RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94
+	Hs
		925723 KDIS_HUMAN (455-623): 6.51e-16: 84.3: 13.45		RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31
+	Hs
		894580 KDIS_HUMAN (455-623): 6.51e-16: 84.3: 13.45		CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00
+	Hs
		951454 KDIS_HUMAN (455-623): 6.51e-16: 84.3: 13.45		RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73
+	Hs
		901042 KDIS_HUMAN (455-623): 6.51e-16: 84.3: 13.45		RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48
+	Hs
		545696 KDIS_HUMAN (455-623): 6.51e-16: 84.3: 13.45		RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75
+	Hs
		436568 KDIS_HUMAN (455-623): 6.51e-16: 84.3: 13.45		RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41
+	Hs
		892676 KDIS_HUMAN (455-623): 6.51e-16: 84.3: 13.45		RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32
+	Hs
		1183607 KDIS_HUMAN (455-623): 6.51e-16: 84.3: 13.45		RHOU_HUMAN (4-186): 1.03e-72: 221: 58.82