HitPredict

Interactor 1: DIRA1 (O95057)
GTP-binding protein Di-Ras1 (Distinct subgroup of the Ras family member 1) (Ras-related inhibitor of cell growth) (Rig) (Small GTP-binding tumor suppressor 1)
Gene: DIRAS1

Interactor 2: RTN4 (Q9NQC3)
Reticulon-4 (Foocen) (Neurite outgrowth inhibitor) (Nogo protein) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5)
Gene: RTN4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 198 Hs			1 1192
+	Hs
		918953 RAB1A_HUMAN (2-196): 7e-80: 238: 28.71		RTN4_HUMAN (1-1192): 3.85e-113: 383: 100.00
+	Hs
		1328148 RAB1B_HUMAN (2-196): 2.09e-79: 236: 28.86		RTN4_HUMAN (1-1192): 3.85e-113: 383: 100.00
+	Hs
		914380 RB11A_HUMAN (3-196): 2.31e-76: 230: 27.27		RTN4_HUMAN (1-1192): 3.85e-113: 383: 100.00
+	Hs
		1079968 RB11B_HUMAN (3-189): 4.76e-75: 226: 29.10		RTN4_HUMAN (1-1192): 3.85e-113: 383: 100.00
+	At
		189211 RAE1A_ARATH (3-196): 5.95e-77: 231: 28.64		RTNLB_ARATH (920-1192): 1.01e-73: 248: 19.36
+	At
		221744 RAA1E_ARATH (3-196): 6.17e-76: 228: 24.40		RTNLB_ARATH (920-1192): 1.01e-73: 248: 19.36
+	At
		189210 RAE1A_ARATH (3-196): 5.95e-77: 231: 28.64		RTNLA_ARATH (992-1192): 3.7e-71: 240: 23.67
+	At
		656920 RAE1C_ARATH (3-196): 1.23e-77: 233: 28.16		RTNLD_ARATH (992-1192): 1.36e-70: 238: 22.75
+	At
		189208 RAE1A_ARATH (3-196): 5.95e-77: 231: 28.64		RTNLD_ARATH (992-1192): 1.36e-70: 238: 22.75
+	Hs
		307040 RAB35_HUMAN (3-196): 3.21e-86: 254: 29.35		RTN3_HUMAN (269-1191): 7.4e-55: 210: 22.06
+	At
		1324948 RAD2B_ARATH (2-196): 2.3e-79: 236: 29.85		RTNLH_ARATH (990-1188): 8.95e-61: 210: 18.54
+	Hs
		307017 RB11A_HUMAN (3-196): 2.31e-76: 230: 27.27		RTN3_HUMAN (269-1191): 7.4e-55: 210: 22.06
+	At
		1341181 RABD1_ARATH (1-196): 3.78e-76: 228: 27.32		RTNLL_ARATH (982-1192): 1.64e-45: 164: 15.02
+	Hs
		897894 RAP1B_HUMAN (7-171): 6.61e-43: 143: 43.11		RTN1_HUMAN (419-1192): 1e-50: 194: 23.36
+	Hs
		297829 RAB35_HUMAN (3-196): 3.21e-86: 254: 29.35		K0754_HUMAN (6-267): 1.47e-10: 68.3: 18.98
+	Hs
		297804 DIRA3_HUMAN (7-198): 1.85e-49: 161: 46.63		K0754_HUMAN (6-267): 1.47e-10: 68.3: 18.98