HitPredict

Interactor 1: RAB7 (O76742)
Ras-related protein Rab7 (DRab7) (EC 3.6.5.2) (Small monomeric GTPase Rab7) (Small ras-like GTPase)
Gene: RAB7

Interactor 2: Q9VLB7 (Q9VLB7)
Rab GDP dissociation inhibitor
Gene: Gdi

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	25453831, 25242320
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	GDI~Ras
Common GO terms	GO:0015031 - protein transport GO:0016192 - vesicle-mediated transport
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 207 Dm			1 443
+	Dm
		197101 O18332_DROME (1-206): 2.56e-85: 252: 30.14		Q9VLB7_DROME (1-443): 0: 692: 100.00
+	Mm
		894618 RAB1A_MOUSE (1-206): 7.34e-88: 259: 30.10		GDIA_MOUSE (1-440): 0: 680: 68.03
+	Dm
		194906 O15971_DROME (1-206): 1.5e-82: 245: 31.40		Q9VLB7_DROME (1-443): 0: 692: 100.00
+	Hs
		724464 RAB1A_HUMAN (1-206): 7.34e-88: 259: 30.10		GDIA_HUMAN (1-440): 0: 678: 67.80
+	Hs
		724515 RAB1B_HUMAN (1-207): 3.42e-87: 257: 30.44		GDIA_HUMAN (1-440): 0: 678: 67.80
+	Hs
		894530 RAB1A_HUMAN (1-206): 7.34e-88: 259: 30.10		GDIB_HUMAN (1-440): 0: 670: 67.80
+	Hs
		894591 RAB1B_HUMAN (1-207): 3.42e-87: 257: 30.44		GDIB_HUMAN (1-440): 0: 670: 67.80
+	Hs
		724451 RAB9A_HUMAN (1-207): 3.06e-83: 247: 47.83		GDIA_HUMAN (1-440): 0: 678: 67.80
+	Hs
		894510 RAB9A_HUMAN (1-207): 3.06e-83: 247: 47.83		GDIB_HUMAN (1-440): 0: 670: 67.80
+	Sc
		376305 YPT1_YEAST (1-207): 9.26e-84: 248: 31.43		GDI1_YEAST (1-443): 0: 585: 53.33
+	Sc
		748744 YPT7_YEAST (1-207): 1.79e-82: 245: 57.55		GDI1_YEAST (1-443): 0: 585: 53.33
+	Sc
		376282 YPT1_YEAST (1-207): 9.26e-84: 248: 31.43		RAEP_YEAST (3-374): 6.21e-121: 366: 26.50
+	Sc
		746356 YPT7_YEAST (1-207): 1.79e-82: 245: 57.55		RAEP_YEAST (3-374): 6.21e-121: 366: 26.50
+	Ce
		96556 O01577_CAEEL (4-204): 1.1e-83: 248: 35.64		E9P8A8_CAEEL (343-442): 6.67e-42: 145: 67.33
+	Hs
		686572 RAB1A_HUMAN (1-206): 7.34e-88: 259: 30.10		RAE2_HUMAN (4-67): 2.77e-13: 73.9: 39.06
+	Hs
		664861 RAB1A_HUMAN (1-206): 7.34e-88: 259: 30.10		RAE1_HUMAN (4-47): 1.13e-12: 71.9: 52.27
+	Hs
		686592 RAB1B_HUMAN (1-207): 3.42e-87: 257: 30.44		RAE2_HUMAN (4-67): 2.77e-13: 73.9: 39.06
+	Hs
		664903 RAB1B_HUMAN (1-207): 3.42e-87: 257: 30.44		RAE1_HUMAN (4-47): 1.13e-12: 71.9: 52.27
+	Hs
		686561 RAB9A_HUMAN (1-207): 3.06e-83: 247: 47.83		RAE2_HUMAN (4-67): 2.77e-13: 73.9: 39.06
+	Hs
		664851 RAB9A_HUMAN (1-207): 3.06e-83: 247: 47.83		RAE1_HUMAN (4-47): 1.13e-12: 71.9: 52.27