HitPredict

Interactor 1: O77434 (O77434)
EG:34F3.8 protein (LD45288p) (Secretory 22, isoform A)
Gene: Sec22

Interactor 2: Q7K0X9 (Q7K0X9)
LD23667p (Syntaxin 7, isoform A) (Syntaxin 7, isoform B)
Gene: Syx7

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	38944040
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	SNARE~Synaptobrevin
Common GO terms	GO:0005484 - SNAP receptor activity GO:0006906 - vesicle fusion GO:0031201 - SNARE complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 211 Dm			1 282
+	Mm
		147440 SC22B_MOUSE (1-211): 2.08e-82: 245: 56.74		STX1A_MOUSE (21-280): 8.42e-55: 180: 18.32
+	Hs
		280135 SC22B_HUMAN (1-211): 2.08e-82: 245: 56.74		STX2_HUMAN (15-280): 1.24e-54: 180: 17.92
+	Hs
		280213 SC22B_HUMAN (1-211): 2.08e-82: 245: 56.74		STX1A_HUMAN (21-280): 4.42e-54: 178: 18.68
+	Dm
		305560 O77434_DROME (1-211): 1.02e-81: 243: 100.00		STX1A_DROME (2-280): 1.42e-53: 177: 19.05
+	Dm
		121793 M9PGI6_DROME (1-211): 4.13e-80: 239: 99.06		STX1A_DROME (2-280): 1.42e-53: 177: 19.05
+	Hs
		280246 SC22B_HUMAN (1-211): 2.08e-82: 245: 56.74		STX12_HUMAN (13-264): 5.65e-51: 170: 31.27
+	Dm
		121799 M9PGI6_DROME (1-211): 4.13e-80: 239: 99.06		Q7K0X9_DROME (1-282): 1.11e-52: 174: 100.00
+	Hs
		189347 SC22B_HUMAN (1-211): 2.08e-82: 245: 56.74		STX7_HUMAN (22-276): 6.13e-48: 162: 38.46
+	At
		1020624 VA721_ARATH (25-198): 3.6e-71: 217: 20.79		SYP22_ARATH (1-265): 5.53e-57: 185: 26.30
+	Hs
		280189 SC22B_HUMAN (1-211): 2.08e-82: 245: 56.74		STX4_HUMAN (10-280): 9.48e-43: 149: 17.67
+	At
		1457166 VA721_ARATH (25-198): 3.6e-71: 217: 20.79		SYP43_ARATH (1-276): 2.22e-51: 172: 17.27
+	Dm
		305594 O77434_DROME (1-211): 1.02e-81: 243: 100.00		Q9VU45_DROME (10-282): 8.47e-42: 146: 23.55
+	At
		265751 VA721_ARATH (25-198): 3.6e-71: 217: 20.79		SYP41_ARATH (1-276): 8.59e-51: 171: 17.27
+	At
		866336 VA722_ARATH (25-198): 6.14e-72: 219: 21.35		SY121_ARATH (4-259): 4.36e-49: 167: 14.60
+	Dm
		121829 M9PGI6_DROME (1-211): 4.13e-80: 239: 99.06		Q9VU45_DROME (10-282): 8.47e-42: 146: 23.55
+	Dm
		305591 O77434_DROME (1-211): 1.02e-81: 243: 100.00		Q9VR90_DROME (18-270): 5.14e-37: 136: 21.79
+	Dm
		121826 M9PGI6_DROME (1-211): 4.13e-80: 239: 99.06		Q9VR90_DROME (18-270): 5.14e-37: 136: 21.79
+	At
		1457227 VA721_ARATH (25-198): 3.6e-71: 217: 20.79		SY122_ARATH (10-259): 4.88e-45: 156: 15.95
+	At
		866323 VA722_ARATH (25-198): 6.14e-72: 219: 21.35		SY111_ARATH (4-259): 9.78e-43: 150: 11.20
+	At
		1192502 VA721_ARATH (25-198): 3.6e-71: 217: 20.79		SY111_ARATH (4-259): 9.78e-43: 150: 11.20