Interactor 1: M3K6 (O95382)
Mitogen-activated protein kinase kinase kinase 6 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 2)
Gene: MAP3K6

Interactor 2: AAPK2 (P54646)
5'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK subunit alpha-2) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31)
Gene: PRKAA2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 20562859
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains AdenylateSensor~Pkinase, Pkinase~Pkinase
Common GO terms GO:0005524 - ATP binding
GO:0006468 - protein phosphorylation
GO:0007165 - signal transduction
GO:0106310 - protein serine kinase activity
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 1288
Hs

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Last updated: 15 Jul 2024