HitPredict

Interactor 1: PCNT (O95613)
Pericentrin (Kendrin) (Pericentrin-B)
Gene: PCNT

Interactor 2: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	26496610, 35914814
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, two hybrid fragment pooling approach
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 3336 Hs			1 245
+	Hs
		317232 PCNT_HUMAN (1-3336): 0: 718: 100.00		1433F_HUMAN (2-240): 1.26e-107: 312: 74.49
+	Hs
		683277 CENPE_HUMAN (1328-3305): 2.89e-65: 250: 10.28		1433B_HUMAN (1-242): 9.01e-140: 393: 87.60
+	Hs
		927475 CP250_HUMAN (1630-3336): 3.41e-53: 210: 10.43		1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00
+	Hs
		909975 CP250_HUMAN (1630-3336): 3.41e-53: 210: 10.43		1433E_HUMAN (2-241): 9.9e-144: 403: 68.18
+	Hs
		647234 CP250_HUMAN (1630-3336): 3.41e-53: 210: 10.43		1433T_HUMAN (1-245): 2.6e-140: 395: 79.59
+	Mm
		926889 PLEC_MOUSE (2-1335): 1.57e-39: 165: 10.63		1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59
+	Zm
		5465 A0A1D6DZK4_MAIZE (1-1237): 1.12e-35: 152: 10.80		B6U284_MAIZE (1-241): 1.06e-142: 401: 63.27
+	Hs
		725130 MYH10_HUMAN (2428-3327): 1.51e-34: 149: 10.93		1433E_HUMAN (2-241): 9.9e-144: 403: 68.18
+	Hs
		927643 MYH2_HUMAN (2483-3325): 3e-34: 147: 12.59		1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00
+	Hs
		522602 MYH7_HUMAN (2483-3316): 1.1e-33: 146: 12.07		1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00
+	Hs
		927055 NUMA1_HUMAN (43-1227): 1.53e-33: 145: 10.92		1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00
+	Hs
		647370 MYH2_HUMAN (2483-3325): 3e-34: 147: 12.59		1433T_HUMAN (1-245): 2.6e-140: 395: 79.59
+	Hs
		522590 MYH7_HUMAN (2483-3316): 1.1e-33: 146: 12.07		1433T_HUMAN (1-245): 2.6e-140: 395: 79.59
+	Hs
		646898 NUMA1_HUMAN (43-1227): 1.53e-33: 145: 10.92		1433T_HUMAN (1-245): 2.6e-140: 395: 79.59
+	Hs
		683667 AKAP9_HUMAN (1605-3329): 1.28e-32: 142: 9.38		1433B_HUMAN (1-242): 9.01e-140: 393: 87.60
+	Hs
		982444 CP250_HUMAN (1630-3336): 3.41e-53: 210: 10.43		1433F_HUMAN (2-240): 1.26e-107: 312: 74.49
+	Hs
		725128 MYH10_HUMAN (2428-3327): 1.51e-34: 149: 10.93		1433G_HUMAN (1-240): 2.37e-108: 314: 74.59
+	Hs
		166698 CE290_HUMAN (1764-3201): 5.48e-34: 147: 10.55		1433F_HUMAN (2-240): 1.26e-107: 312: 74.49
+	Hs
		905044 AKAP9_HUMAN (1605-3329): 1.28e-32: 142: 9.38		1433G_HUMAN (1-240): 2.37e-108: 314: 74.59
+	Hs
		684294 AKAP9_HUMAN (1605-3329): 1.28e-32: 142: 9.38		1433S_HUMAN (1-237): 8.27e-104: 302: 71.97