HitPredict

Interactor 1: RHBT1 (O94844)
Rho-related BTB domain-containing protein 1
Gene: RHOBTB1

Interactor 2: EZRI (P15311)
Ezrin (Cytovillin) (Villin-2) (p81)
Gene: EZR

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	37575477
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FERM_M~Ras
Common GO terms	GO:0005886 - plasma membrane GO:0008360 - regulation of cell shape GO:0042995 - cell projection
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 696 Hs			1 586
+	Mm
		683938 SPOP_MOUSE (300-648): 4.67e-73: 242: 15.32		EZRI_MOUSE (1-586): 1.55e-176: 514: 96.59
+	Hs
		582741 RAC1_HUMAN (12-219): 3.84e-73: 236: 35.55		EZRI_HUMAN (1-586): 5.69e-178: 517: 100.00
+	Mm
		683960 SPOP_MOUSE (300-648): 4.67e-73: 242: 15.32		RADI_MOUSE (1-586): 1.52e-164: 483: 76.28
+	Hs
		767417 RAC1_HUMAN (12-219): 3.84e-73: 236: 35.55		RADI_HUMAN (1-586): 7.86e-165: 484: 76.28
+	Hs
		767151 CDC42_HUMAN (12-218): 1.56e-89: 279: 37.14		MERL_HUMAN (2-586): 3.19e-146: 436: 44.37
+	Mm
		683947 SPOP_MOUSE (300-648): 4.67e-73: 242: 15.32		MOES_MOUSE (1-586): 2.82e-160: 472: 72.36
+	Hs
		955625 CDC42_HUMAN (12-218): 1.56e-89: 279: 37.14		E41L5_HUMAN (5-586): 7.73e-142: 430: 21.28
+	Hs
		601189 RHOQ_HUMAN (10-213): 9.09e-84: 264: 37.68		MERL_HUMAN (2-586): 3.19e-146: 436: 44.37
+	Hs
		601454 RHOQ_HUMAN (10-213): 9.09e-84: 264: 37.68		E41L5_HUMAN (5-586): 7.73e-142: 430: 21.28
+	Hs
		767160 RAC1_HUMAN (12-219): 3.84e-73: 236: 35.55		MERL_HUMAN (2-586): 3.19e-146: 436: 44.37
+	Hs
		955581 CDC42_HUMAN (12-218): 1.56e-89: 279: 37.14		E41LB_HUMAN (4-554): 6.83e-121: 380: 17.59
+	Hs
		955593 CDC42_HUMAN (12-218): 1.56e-89: 279: 37.14		E41L1_HUMAN (3-524): 3.55e-119: 375: 23.06
+	Hs
		955785 CDC42_HUMAN (12-218): 1.56e-89: 279: 37.14		FARP1_HUMAN (3-549): 1.98e-117: 375: 19.07
+	Hs
		955769 CDC42_HUMAN (12-218): 1.56e-89: 279: 37.14		E41L3_HUMAN (2-466): 2.18e-114: 367: 22.83
+	Hs
		601444 RHOQ_HUMAN (10-213): 9.09e-84: 264: 37.68		E41L1_HUMAN (3-524): 3.55e-119: 375: 23.06
+	Hs
		601516 RHOQ_HUMAN (10-213): 9.09e-84: 264: 37.68		FARP1_HUMAN (3-549): 1.98e-117: 375: 19.07
+	Hs
		601509 RHOQ_HUMAN (10-213): 9.09e-84: 264: 37.68		E41L3_HUMAN (2-466): 2.18e-114: 367: 22.83
+	Mm
		266875 SPOP_MOUSE (300-648): 4.67e-73: 242: 15.32		E41L2_MOUSE (2-577): 3.86e-120: 380: 19.56
+	Mm
		266872 RAC1_MOUSE (12-219): 3.84e-73: 236: 35.55		E41L2_MOUSE (2-577): 3.86e-120: 380: 19.56
+	Hs
		988700 RAC1_HUMAN (12-219): 3.84e-73: 236: 35.55		E41LB_HUMAN (4-554): 6.83e-121: 380: 17.59